Blue light impairs the repair of UVB‐induced pyrimidine dimers in a human skin model

T Douki, D Bacqueville, C Jacques… - Photochemistry and …, 2024 - Wiley Online Library
In recent years, interest is growing in the biological cutaneous effects of high‐energy visible
light (400–450 nm). In the present study, we explored the impact of blue light (BL) on the …

An important step towards the comprehensive sun protection: Blue‐light exposure inhibits DNA repair in reconstituted human skin and a broadband sunscreen avoids …

PN Tonolli, MS Baptista - 2024 - Wiley Online Library
The field of sun protection is quickly changing and the research article by Douki et al.,
published in the current issue of Photochemistry and Photobiology, reported key …

Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

RP Gajula, S Gaddameedhi - Frontiers in Physiology, 2015 - frontiersin.org
Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the
western world (Bowden, 2004). Frequency of its occurrence is closely associated with skin …

Blue light induces DNA damage in normal human skin keratinocytes

C Chamayou‐Robert, C DiGiorgio… - Photodermatology …, 2022 - Wiley Online Library
Background The generation of DNA damage by ultra‐violet radiations (UV) is well
established, and both the nature of the DNA lesions and their respective DNA repair …

Pyrimidine dimer formation by UVA radiation: implications for photoreactivation

BM Sutherland, H Hacham, JC Sutherland, RW Gange - 1991 - osti.gov
The duality of biological and biochemical effects mediated by UVA radiation complicates
evaluation of its biological role. On the one hand, UVA can drive photoreactivation and …

Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations

S Courdavault, C Baudouin, M Charveron… - DNA repair, 2005 - Elsevier
Induction of DNA damage by solar UV radiation is a key event in the development of skin
cancers. Bipyrimidine photoproducts, including cyclobutane pyrimidine dimers (CPDs),(6-4) …

PHOTOREPAIR OF PYRIMIDINE DIMERS IN HUMAN SKIN IN VIVO

SM D'Ambrosio, JW Whetstone… - Photochemistry and …, 1981 - Wiley Online Library
The exposure of human skin in vivo to UV radiation emitted from a sunlamp induces the
formation of pyrimidine dimers. The number of dimers, as detected by UV‐endonuclease …

Ultraviolet B Radiation-Induced DNA Lesions in Mouse Epidermis: An Assessment Using a Novel32P-Postlabelling Technique

ML Chatterjee, R Agarwal, H Mukhtar - Biochemical and biophysical …, 1996 - Elsevier
Ultraviolet B (UVB) component of the sunlight is the major cause of nonmelanoma skin
cancer (NMSC) in humans. UVB is absorbed directly by cellular DNA and produces lesions …

Enhancement of UVB-induced DNA damage repair after a chronic low-dose UVB pre-stimulation

MCD Desgarnier, PJ Rochette - DNA repair, 2018 - Elsevier
Absorption of solar ultraviolet (UV) radiation by DNA leads to the formation of the highly
mutagenic cyclobutane pyrimidine dimer (CPD). The mutagenicity of CPD is caused, in part …

In vivo induction of pyrimidine dimers in human skin by UVA radiation: initiation of cell damage and/or intercellular communication?

LA Applegate, C Scaletta… - International …, 1999 - spandidos-publications.com
Pyrimidine dimers participate as important factors in ultraviolet-induced lethality,
mutagenicity and tumorgenicity. Substantial efforts have been made in recent years to …