Delivering functional imaging on the MRI-linac: current challenges and potential solutions

A Datta, MC Aznar, M Dubec, GJM Parker… - Clinical Oncology, 2018 - Elsevier
Magnetic resonance imaging (MRI) is a highly versatile imaging modality that can be used to
measure features of the tumour microenvironment including cell death, proliferation …

Towards accurate and precise image-guided radiotherapy: clinical applications of the MR-Linac

JW Randall, N Rammohan, IJ Das, P Yadav - Journal of Clinical …, 2022 - mdpi.com
Advances in image-guided radiotherapy have brought about improved oncologic outcomes
and reduced toxicity. The next generation of image guidance in the form of magnetic …

Quantitative MRI on MR-Linacs: Towards Biological Image-Guided Adaptive Radiotherapy

PJ van Houdt, S Li, Y Yang… - Seminars in Radiation …, 2024 - Elsevier
Recognizing the potential of quantitative imaging biomarkers (QIBs) in radiotherapy, many
studies have investigated the prognostic value of quantitative MRI (qMRI). With the …

MRI-LINAC: A transformative technology in radiation oncology

J Ng, F Gregucci, RT Pennell, H Nagar… - Frontiers in …, 2023 - frontiersin.org
Advances in radiotherapy technologies have enabled more precise target guidance,
improved treatment verification, and greater control and versatility in radiation delivery …

Quantitative magnetic resonance imaging for biological image-guided adaptive radiotherapy

PJ Van Houdt, Y Yang, UA Van der Heide - Frontiers in Oncology, 2021 - frontiersin.org
MRI-guided radiotherapy systems have the potential to bring two important concepts in
modern radiotherapy together: adaptive radiotherapy and biological targeting. Based on …

The Australian magnetic resonance imaging–linac program

PJ Keall, M Barton, S Crozier - Seminars in radiation oncology, 2014 - Elsevier
The Australian magnetic resonance imaging (MRI)–Linac program is a $16-million
government-funded project to advance the science and clinical practice of exquisite real …

MR-guidance in clinical reality: current treatment challenges and future perspectives

S Corradini, F Alongi, N Andratschke, C Belka… - Radiation …, 2019 - Springer
Abstract Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new
era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct …

History of technological advancements towards MR-Linac: the future of image-guided radiotherapy

N Rammohan, JW Randall, P Yadav - Journal of Clinical Medicine, 2022 - mdpi.com
Image-guided radiotherapy (IGRT) enables optimal tumor targeting and sparing of organs-at-
risk, which ultimately results in improved outcomes for patients. Magnetic resonance …

[HTML][HTML] Technical design and concept of a 0.35 T MR-Linac

S Klüter - Clinical and translational radiation oncology, 2019 - Elsevier
The integration of magnetic resonance (MR) imaging and linear accelerators into hybrid
treatment systems has made MR-guided radiation therapy a clinical reality. This work …

MRI-guided radiation therapy: an emerging paradigm in adaptive radiation oncology

R Otazo, P Lambin, JP Pignol, ME Ladd… - Radiology, 2021 - pubs.rsna.org
Radiation therapy (RT) continues to be one of the mainstays of cancer treatment.
Considerable efforts have been recently devoted to integrating MRI into clinical RT planning …