[HTML][HTML] The potential for Lactoferrin to reduce SARS-CoV-2 induced cytokine storm

M Zimecki, JK Actor, ML Kruzel - International immunopharmacology, 2021 - Elsevier
The COVID-19 pandemic is a serious global health threat caused by severe acute
respiratory syndrome of coronavirus 2 (SARS-CoV-2). Symptoms of COVID-19 are highly …

Lactoferrin for COVID-19 prevention, treatment, and recovery

E Bolat, F Eker, M Kaplan, H Duman, A Arslan… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), a unique beta-
coronavirus, has caused the most serious outbreak of the last century at the global level …

Lactoferrin as potential preventative and adjunct treatment for COVID-19

R Chang, TB Ng, WZ Sun - International Journal of Antimicrobial Agents, 2020 - Elsevier
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic is rapidly advancing
across the globe despite drastic public and personal health measures. Antivirals and …

The influence of viral infections on iron homeostasis and the potential for lactoferrin as a therapeutic in the age of the SARS-CoV-2 pandemic

JL Ward, M Torres-Gonzalez, MCB Ammons - Nutrients, 2022 - mdpi.com
The association of hyperinflammation and hyperferritinemia with adverse outcomes in SARS-
CoV-2-infected patients suggests an integral role for iron homeostasis in pathogenesis, a …

Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences

E Campione, C Lanna, T Cosio, L Rosa… - Frontiers in …, 2021 - frontiersin.org
Lactoferrin (Lf) is a cationic glycoprotein synthetized by exocrine glands and is present in all
human secretions. It is also secreted by neutrophils in infection and inflammation sites. This …

An overview on in vitro and in vivo antiviral activity of lactoferrin: its efficacy against SARS-CoV-2 infection

L Rosa, A Cutone, MP Conte, E Campione, L Bianchi… - Biometals, 2023 - Springer
Beyond the absolute and indisputable relevance and efficacy of anti-SARS-CoV-2 vaccines,
the rapid transmission, the severity of infection, the absence of the protection on …

Protective effects of lactoferrin against SARS-CoV-2 infection in vitro

C Salaris, M Scarpa, M Elli, A Bertolini, S Guglielmetti… - Nutrients, 2021 - mdpi.com
SARS-CoV-2 is a newly emerging virus that currently lacks curative treatments. Lactoferrin
(LF) is a naturally occurring non-toxic glycoprotein with broad-spectrum antiviral …

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19

JK Mann, T Ndung'u - Future Virology, 2020 - Taylor & Francis
Coronavirus disease 2019 (COVID-19), caused by SARS coronavirus 2 (SARS-CoV-2), is
spreading rapidly with no established effective treatments. While most cases are mild, others …

[HTML][HTML] The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

HM Habib, S Ibrahim, A Zaim, WH Ibrahim - Biomedicine & …, 2021 - Elsevier
Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19.
Indeed, several of the manifestations of COVID-19, such as inflammation, hypercoagulation …

The prospect of lactoferrin use as adjunctive agent in management of SARS-CoV-2 patients: A randomized pilot study

FD Algahtani, MT Elabbasy, MA Samak, AA Adeboye… - Medicina, 2021 - mdpi.com
Background and Objectives: Preventive, adjunctive and curative properties of lactoferrin
have been evaluated since the first wave of severe acute respiratory syndrome coronavirus …