The GTP switch of the small G-protein Arf1 (ADP-ribosylation factor 1) on lipid membranes
promotes the polymerization of the COPI (coat protein complex I) coat, which acts as a …

ArfGAP1, which promotes GTP hydrolysis on the small G protein Arf1 on Golgi membranes,
interacts preferentially with positively curved membranes through its amphipathic lipid …

The GTPase Arf1 is considered as a molecular switch that regulates binding and release of
coat proteins that polymerize on membranes to form transport vesicles. Here, we show that …

ArfGAP1 (Arf GTPase activating protein 1) controls the cycling of the COPI coat on Golgi
membranes by catalyzing GTP hydrolysis in the small G protein Arf1. ArfGAP1 contains a …

Formation of coated vesicles requires two striking manipulations of the lipid bilayer. First,
membrane curvature is induced to drive bud formation. Second, a scission reaction at the …

Dimerization of the small GTPase Arf is prerequisite for the scission of COPI‐coated
transport vesicles. Here, we quantify the monomer/dimer equilibrium of Arf within the …

The selective transfer of material between membrane-delimited organelles is mediated by
protein-coated vesicles. In many instances, formation of membrane trafficking intermediates …

Protein coats deform flat lipid membranes into buds and capture membrane proteins to form
transport vesicles,,. The assembly/disassembly cycle of the COPI coat on Golgi membranes …

ArfGAP1 promotes GTP hydrolysis in Arf1, a small G protein that interacts with lipid
membranes and drives the assembly of the COPI coat in a GTP‐dependent manner. The …

ADP-ribosylation factor 1 (Arf1) plays an important role in early and intra-Golgi protein
trafficking. During this process, Arf1 interacts with many different proteins and other …