Autophagy has a complex dual role in tumor survival or cell death owning to that is an
evolutionarily conserved catabolic mechanism and provides the cells with a sustainable …

Autophagy is a major intracellular pathway involving in the degradation and recycling of
cytosolic material, including organelles, proteins, and ribosomes. Autophagy is commonly …

Mild hyperthermia enhances anti-cancer effects of chemotherapy, but the precise
biochemical mechanisms involved are not clear. This study was carried out to investigate …

The occurrence and mechanisms of autophagy induced by heat stress are not well known in
lung cancer cells. Here, we have demonstrated that heat stress induces autophagy in A549 …

A general feature of cancer is hypoxia, determined as low oxygen levels. Low oxygen levels
may cause cells to alter in ways that contribute to tumor growth and resistance to treatment …

Adenoid cystic carcinoma (ACC) is one of the most common types of salivary gland
malignancy in the head and neck, and its aggressive ability to invade and metastasize is an …

Hypoxia occurs in a wide variety of physiological and pathological conditions, including
tumorigenesis. Tumor cells have to adapt to hypoxia by altering their gene expression and …

The pleiotropic effects of hyperthermia on cancer cells have been well documented, and
microwave hyperthermia (MWHT) has been widely applied for multifarious cancer treatment …

Proteostasis mechanisms, such as proteotoxic-stress response and autophagy, are
increasingly recognized for their roles in influencing various cancer hallmarks such as …

Background Oral squamous cell carcinoma (OSCC) is one of the most common forms of oral
cancer and is known to have poor prognostic outcomes. Autophagy is known to be …