A narrative review of gut-muscle axis and sarcopenia: The potential role of gut microbiota

J Zhao, Y Huang, X Yu - International Journal of General Medicine, 2021 - Taylor & Francis
Sarcopenia is a multifactorial disease related to aging, chronic inflammation, insufficient
nutrition, and physical inactivity. Previous studies have suggested that there is a relationship …

Understanding the gut microbiota and sarcopenia: a systematic review

C Liu, WH Cheung, J Li, SKH Chow… - Journal of cachexia …, 2021 - Wiley Online Library
Background Gut microbiota dysbiosis and sarcopenia commonly occur in the elderly.
Although the concept of the gut–muscle axis has been raised, the casual relationship is still …

Sarcopenia is a cause and consequence of metabolic dysregulation in aging humans: effects of gut dysbiosis, glucose dysregulation, diet and lifestyle

JW Daily, S Park - Cells, 2022 - mdpi.com
Skeletal muscle mass plays a critical role in a healthy lifespan by helping to regulate
glucose homeostasis. As seen in sarcopenia, decreased skeletal muscle mass impairs …

Skeletal muscle-gut axis: emerging mechanisms of sarcopenia for intestinal and extra intestinal diseases.

R De Sire, G Rizzatti, F Ingravalle… - Minerva …, 2018 - europepmc.org
In recent years, there has been an increasing interest on muscle wasting, considering the
reduction of quality of life and the increase of morbidity and mortality associated. Sarcopenia …

Gut microbiota as a promising therapeutic target for age-related sarcopenia

T Zhang, J Cheng, Y Hu - Ageing research reviews, 2022 - Elsevier
Sarcopenia is characterized by a progressive loss of skeletal muscle mass and function with
aging. Recently, sarcopenia has been shown to be closely related with gut microbiota …

Aging gut microbiota at the cross-road between nutrition, physical frailty, and sarcopenia: is there a gut–muscle axis?

A Ticinesi, F Lauretani, C Milani, A Nouvenne, C Tana… - Nutrients, 2017 - mdpi.com
Inadequate nutrition and physical inactivity are the mainstays of primary sarcopenia–
physiopathology in older individuals. Gut microbiota composition is strongly dependent on …

Gut microbiota, muscle mass and function in aging: a focus on physical frailty and sarcopenia

A Ticinesi, A Nouvenne, N Cerundolo, P Catania… - Nutrients, 2019 - mdpi.com
Human gut microbiota is able to influence the host physiology by regulating multiple
processes, including nutrient absorption, inflammation, oxidative stress, immune function …

Inflammatory bowel diseases and sarcopenia: the role of inflammation and gut microbiota in the development of muscle failure

OM Nardone, R de Sire, V Petito, A Testa… - Frontiers in …, 2021 - frontiersin.org
Sarcopenia represents a major health burden in industrialized country by reducing
substantially the quality of life. Indeed, it is characterized by a progressive and generalized …

Exploring the Preventive Effect and Mechanism of Senile Sarcopenia Based on “Gut–Muscle Axis”

X Liao, M Wu, Y Hao, H Deng - Frontiers in bioengineering and …, 2020 - frontiersin.org
Age-related sarcopenia probably leads to chronic systemic inflammation and plays a vital
role in the development of the complications of the disease. Gut microbiota, an …

Targeting the gut microbiota to improve dietary protein efficacy to mitigate sarcopenia

E de Marco Castro, CH Murphy, HM Roche - Frontiers in Nutrition, 2021 - frontiersin.org
Sarcopenia is characterised by the presence of diminished skeletal muscle mass and
strength. It is relatively common in older adults as ageing is associated with anabolic …