Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in
the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
Patients with COVID-19 who require ICU admission might have the cytokine storm. It is a
state of out-of-control release of a variety of inflammatory cytokines. The molecular …

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[PDF][PDF] Cytokine storms: understanding COVID-19

N Mangalmurti, CA Hunter - Immunity, 2020 - cell.com
The elevated circulating levels of cytokines associated with a variety of infectious and
immune-mediated conditions are frequently termed a cytokine storm. Here, we explain the …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

[HTML][HTML] Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position …

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …