Background If percutaneous coronary intervention (PCI) is required in patients taking oral
anticoagulants, antiplatelet therapy with aspirin and clopidogrel is indicated, but such triple …

Background Dual antiplatelet therapy with clopidogrel plus low-dose aspirin has not been
studied in a broad population of patients at high risk for atherothrombotic events. Methods …

Background: Although clopidogrel plus aspirin is more effective than aspirin alone in
preventing subsequent vascular events in patients with unstable angina, the cost …

Aims Immediate treatment with a loading dose of clopidogrel at diagnosis of ST-segment
elevation myocardial infarction (STEMI) is recommended by ESC/AHA/ACC guidelines in …

Background—The main goal of the initial treatment of ST-segment elevation myocardial
infarction is prompt reperfusion of the infarct-related artery. The value of pretreatment with …

Platelets play a central role in both the short-and long-term manifestations of
atherothrombosis. In acute coronary syndrome (ACS), there is a steep rise in cardiovascular …

Objective The objective of this study was to provide a comprehensive comparison of the long
term safety and tolerability of clopidogrel, a new adenosine diphosphate (ADP) receptor …

Background Dual-antiplatelet therapy with aspirin and a thienopyridine is a cornerstone of
treatment to prevent thrombotic complications of acute coronary syndromes and …

Background Both aspirin and clopidogrel reduce the rate of cardiovascular events in
patients with coronary heart disease. We estimated the cost effectiveness of the increased …

OBJECTIVES: To examine the clinical effectiveness and cost-effectiveness of two alternative
antiplatelet agents, clopidogrel and modified-release (MR)-dipyridamole, relative to …