We aimed to verify whether DHEA, a neuoroactive neurosteroid, has a protective role in
preventing the occurrence or enhancement of the severity of depression and anxiety in mice …

Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, exert multiple effects in the
rodent central nervous system (CNS). Most of them seem to be mediated through their non …

Alterations in the levels of dehydroepiandrosterone (DHEA) in the brain can allosterically
modulate γ-aminobutyric-acid-type-A (GABA AR), N-methyl-D-aspartate (NMDAR), and …

Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are neurosteroids that have been
shown to interact with the GABA system. The present study examined the effects of these …

In response to lipopolysaccharide (LPS), macrophages secrete cytokines that transmit a
message to the brain and induce sickness behavior. Because dehydroepiandrosterone …

The effects of Dehydroepiandrosterone (DHEA) and its sulfate ester,
Dehydroepiandrosterone sulfate (DHEAS) on performance in various cognitive and affective …

Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, are the most abundant
steroid hormones in the humans. However, their physiological significance, their …

It is well-documented that dehydroepiandrosterone (DHEA) exhibits various behavioral
effects in rodents, at least one of which is modulation of learning/memory processes in …

Previous pre-clinical and clinical studies investigating the antidepressant potential of DHEA
revealed conflicting results. In this study, the effects of exogenous DHEA on performance in …

Outbred Sprague-Dawley rats exhibit considerable heterogeneity within a population when
evaluated for a variety of biologic functions, such as dietary fat intake, alcohol preference …