Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats

SK Nalabotu, MB Kolli, WE Triest, JY Ma… - International journal …, 2011 - Taylor & Francis
Background Cerium oxide (CeO2) nanoparticles have been posited to have both beneficial
and toxic effects on biological systems. Herein, we examine if a single intratracheal …

The acute pulmonary and thrombotic effects of cerium oxide nanoparticles after intratracheal instillation in mice

A Nemmar, S Al-Salam, S Beegam… - International journal …, 2017 - Taylor & Francis
Cerium oxide nanoparticles (CeO2 NPs), used as a diesel fuel catalyst, can be emitted into
the ambient air, resulting in exposure to humans by inhalation. Recent studies have reported …

Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats

JY Ma, H Zhao, RR Mercer, M Barger, M Rao… - …, 2011 - Taylor & Francis
The use of cerium compounds as diesel fuel catalyst results in the emission of cerium oxide
nanoparticles (CeO2) in the exhaust. This study characterized the potential effects of CeO2 …

Cerium oxide nanoparticles in lung acutely induce oxidative stress, inflammation, and DNA damage in various organs of mice

A Nemmar, P Yuvaraju, S Beegam… - Oxidative medicine …, 2017 - Wiley Online Library
CeO2 nanoparticles (CeO2 NPs) which are used as a diesel fuel additive are emitted in the
particulate phase in the exhaust, posing a health concern. However, limited information …

Bio‐distribution and in vivo antioxidant effects of cerium oxide nanoparticles in mice

SM Hirst, A Karakoti, S Singh, W Self… - Environmental …, 2013 - Wiley Online Library
Cerium oxide nanoparticles have oxygen defects in their lattice structure that enables them
to act as a regenerative free radical scavenger in a physiological environment. We …

Acute inhalation toxicity of cerium oxide nanoparticles in rats

A Srinivas, PJ Rao, G Selvam, PB Murthy, PN Reddy - Toxicology letters, 2011 - Elsevier
The aim of the present study was to assess the acute toxic potential of cerium oxide
nanoparticles (CeO2 NPs) in rats when exposed through the head and nose inhalation …

[HTML][HTML] Pulmonary toxicity of well-dispersed cerium oxide nanoparticles following intratracheal instillation and inhalation

Y Morimoto, H Izumi, Y Yoshiura, T Tomonaga… - Journal of Nanoparticle …, 2015 - Springer
We performed inhalation and intratracheal instillation studies of cerium dioxide (CeO 2)
nanoparticles in order to investigate their pulmonary toxicity, and observed pulmonary …

Cerium oxide nanoparticles: advances in biodistribution, toxicity, and preclinical exploration

E Casals, M Zeng, M Parra‐Robert, G Fernández‐Varo… - Small, 2020 - Wiley Online Library
Antioxidant nanoparticles have recently gained tremendous attention for their enormous
potential in biomedicine. However, discrepant reports of either medical benefits or toxicity …

Toxicity and tissue distribution of cerium oxide nanoparticles in rats by two different routes: single intravenous injection and single oral administration

K Park, J Park, H Lee, J Choi, WJ Yu, J Lee - Archives of pharmacal …, 2018 - Springer
Toxicity and target organ distribution of cerium oxide nanoparticles (CeNPs) were
investigated via single intravenous injection and single oral administration, respectively …

Toxicity and bio-accumulation of inhaled cerium oxide nanoparticles in CD1 mice

S Aalapati, S Ganapathy, S Manapuram… - …, 2014 - Taylor & Francis
Male CD1 mice were subjected to nose-inhalation exposure of CeO2 nanoparticles (NPs)
for 0, 7, 14 or 28 days with 14 or 28 days of recovery time at an aerosol concentration of 2 …