[HTML][HTML] Cytokine storm syndrome in severe COVID-19

P Ruscitti, O Berardicurti, A Iagnocco… - Autoimmunity …, 2020 - ncbi.nlm.nih.gov
Dear Editor, we read with interest the article by McGonagle et al., which has been recently
published on this Journal [1]. This article highlights the role of pro-inflammatory cytokines in …

COVID-19: consider cytokine storm syndromes and immunosuppression

P Mehta, DF McAuley, M Brown, E Sanchez… - The lancet, 2020 - thelancet.com
As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been con firmed in 125
048 people worldwide, carrying a mortality of approximately 3· 7%, 1 compared with a …

COVID-19 cytokine storm syndrome: a threshold concept

LYC Chen, TTT Quach - The Lancet Microbe, 2021 - thelancet.com
The COVID-19 pandemic has placed the practice of medicine at a threshold overlooking a
new and different era, 1 and has led to the evolving concept of COVID-19 cytokine storm …

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

X Yongzhi - Emerging microbes & infections, 2021 - Taylor & Francis
ABSTRACT SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19
patients experience sudden and rapid deterioration with the onset of fatal cytokine storm …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease

D McGonagle, K Sharif, A O'Regan, C Bridgewood - Autoimmunity reviews, 2020 - Elsevier
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-
inflammation designated under the umbrella term of macrophage activation syndrome …

[HTML][HTML] Cytokine release syndrome is not usually caused by secondary hemophagocytic lymphohistiocytosis in a cohort of 19 critically ill COVID-19 patients

G Lorenz, P Moog, Q Bachmann, P La Rosee… - Scientific reports, 2020 - nature.com
Severe COVID-19 associated respiratory failure, poses the one challenge of our days.
Assessment and treatment of COVID-19 associated hyperinflammation may be key to …

The rheumatologist's role in COVID-19

RQ Cron, WW Chatham - The Journal of rheumatology, 2020 - jrheum.org
The novel coronavirus (severe acute respiratory syndrome; SARS-CoV-2) pandemic has
spread rapidly throughout the planet. It is believed to have originated in the Wuhan province …

Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …