Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies

M Cancio, R Ciccocioppo, PRM Rocco, BL Levine… - Cytotherapy, 2020 - Elsevier
Abstract Coronavirus disease 2019 (SARS-CoV2) is an active global health threat for which
treatments are desperately being sought. Even though most people infected experience mild …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

Cytokine storm syndrome in coronavirus disease 2019: A narrative review

YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
Cytokine storm syndrome (CSS) is a critical clinical condition induced by a cascade of
cytokine activation, characterized by overwhelming systemic inflammation …

[HTML][HTML] Autoimmunity as the comet tail of COVID-19 pandemic

R Talotta, E Robertson - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can give rise to
different clinical manifestations that are directly related to viral tissue damage or indirectly …

SARS‐CoV‐2 infection as a trigger of autoimmune response

MC Sacchi, S Tamiazzo, P Stobbione… - Clinical and …, 2021 - Wiley Online Library
Currently, few evidences have shown the possible involvement of autoimmunity in patients
affected by coronavirus disease 2019 (COVID‐19). In this study, we elucidate whether …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome

LYC Chen, RL Hoiland, S Stukas… - European …, 2020 - Eur Respiratory Soc
The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome
(COVID-CSS) emerged early in the severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Immunologic features in coronavirus disease 2019: functional exhaustion of T cells and cytokine storm

S Mahmoudi, M Rezaei, N Mansouri, M Marjani… - Journal of clinical …, 2020 - Springer
To the Editor: Since the emergence of Coronavirus Disease 2019 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the …

[HTML][HTML] Hemophagocytic lymphohistiocytosis: a review inspired by the COVID-19 pandemic

M Soy, P Atagündüz, I Atagündüz, GT Sucak - Rheumatology international, 2021 - Springer
Hemophagocytic syndrome (HPS) or hemophagocytic lymphohistiocytosis (HLH) is an acute
and rapidly progressive systemic inflammatory disorder characterized by cytopenia …

[HTML][HTML] Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study

BJ Webb, ID Peltan, P Jensen, D Hoda… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …