A two-stage “tandem strategy” for the regiocontrolled synthesis of very highly substituted
quinolines is described. Benzannulation based on the reaction of cyclobutenones or diazo …

β-(2-aminophenyl)-α, β-ynones can quickly give functionalized 2, 4-disubstituted quinolines
through tandem nucleophic addition/annulations reactions. Acid-catalysed cyclization of β-(2 …

A practical Cu-catalyzed cascade cyclization of o-halobenzoate with enaminones to
construct isoquinolinone derivatives is described. The process involves a Cu-catalyzed …

A practical route to quinoline from anilines through acid-mediated cyclization of 3-(N-aryl-N-
sulfonylamino) propionaldehydes has been developed. Treatment of the cyclization …

With triethylamine as a vinylene source, a convenient protocol for the regioselective
synthesis of β, γ-nonsubstituted 2-arylquinolines from aldehydes and arylamines has been …

An efficient and rapid synthesis of multiply substituted quinolines is described. This method
is enabled by a three-component cascade annulation of readily available aryl diazonium …

An approach of general applicability to diverse quinolines and isoquinolines via a tactic that
utilizes the recursive anion from nitromethane as a 1C-connector to stitch easily and …

An acid-promoted cyclization of α-azidobenzyl ketones has been developed for the
synthesis of 6-substituted quinoline derivatives. A variety of synthetically useful 6-OTf or …

The use of a powerful aminobenzannulation reaction has been applied for the synthesis of
amino-substituted quinolines, dibenzofurans, and carbazoles. The precursors are …

An effective electrophilic annulation reaction of azacyclic ynones was reported, divergently
affording various functionalized 3-iodo-2H-quinolizin-2-ones and 1, 3-diiodo-2H-quinolizin-2 …