RNA interference of an orthologue of Dicer of Meloidogyne incognita alludes to the gene's importance in nematode development
Dicers and dicer-like enzymes play an essential role in small RNA processing in eukaryotes.
Nematodes are thought to encode one dicer, DCR-1; only that for Caenorhabditis spp. is …
Nematodes are thought to encode one dicer, DCR-1; only that for Caenorhabditis spp. is …
Phylogenetic analysis of the endoribonuclease Dicer family
Dicers are proteins of the ribonuclease III family with the ability to process dsRNA, involved
in regulation of gene expression at the post-transcriptional level. Dicers are conserved from …
in regulation of gene expression at the post-transcriptional level. Dicers are conserved from …
Multiple Dicer Genes in the Early-Diverging Metazoa
Dicer proteins are highly conserved, are present in organisms ranging from plants to
metazoans, and are essential components of the RNA interference pathway. Although the …
metazoans, and are essential components of the RNA interference pathway. Although the …
The molecular architecture of human Dicer
Dicer is a multidomain enzyme that generates small RNAs for gene silencing in eukaryotes.
Current understanding of Dicer structure is restricted to simple forms of the enzyme, whereas …
Current understanding of Dicer structure is restricted to simple forms of the enzyme, whereas …
Genetic insight into the domain structure and functions of dicer-type ribonucleases
K Ciechanowska, M Pokornowska… - International journal of …, 2021 - mdpi.com
Ribonuclease Dicer belongs to the family of RNase III endoribonucleases, the enzymes that
specifically hydrolyze phosphodiester bonds found in double-stranded regions of RNAs …
specifically hydrolyze phosphodiester bonds found in double-stranded regions of RNAs …
Short interfering RNA-mediated knockdown of drosha and pasha in undifferentiated Meloidogyne incognita eggs leads to irregular growth and embryonic lethality
JJ Dalzell, ND Warnock, MA Stevenson… - International journal for …, 2010 - Elsevier
Micro-(mi) RNAs play a pivotal role in the developmental regulation of plants and animals.
We reasoned that disruption of normal heterochronic activity in differentiating Meloidogyne …
We reasoned that disruption of normal heterochronic activity in differentiating Meloidogyne …
Structure of Dicer and mechanistic implications for RNAi
Dicer is a specialized ribonuclease that processes double-stranded RNA (dsRNA) into small
RNA fragments about25 nucleotides in length during the initiation phase of RNA …
RNA fragments about25 nucleotides in length during the initiation phase of RNA …
Dicer structure and function: conserved and evolving features
D Zapletal, K Kubicek, P Svoboda, R Stefl - EMBO reports, 2023 - embopress.org
RNase III Dicer produces small RNAs guiding sequence‐specific regulations, with important
biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference …
biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference …
Biochemical characterization of the dicing activity of Dicer-like 2 in the model filamentous fungus Neurospora crassa
Dicing of double-stranded RNA (dsRNA) into small RNA is an essential process to trigger
transcriptional and post-transcriptional gene silencing. Using cell-free extracts of the model …
transcriptional and post-transcriptional gene silencing. Using cell-free extracts of the model …
The Significance of the DUF283 Domain for the Activity of Human Ribonuclease Dicer
A Szczepanska, M Wojnicka… - International Journal of …, 2021 - mdpi.com
Dicers are multidomain proteins, usually comprising an amino-terminal putative helicase
domain, a DUF283 domain (domain of unknown function), a PAZ domain, two RNase III …
domain, a DUF283 domain (domain of unknown function), a PAZ domain, two RNase III …