Objective To determine whether chronic motor deficits secondary to traumatic brain injury
(TBI) can be improved by implantation of allogeneic modified bone marrow–derived …

Mesenchymal stromal cells (MSCs) are widely used in preclinical models of traumatic brain
injury (TBI). Results are promising in terms of neurological improvement but are hampered …

Background and Purpose—Preclinical data suggest that cell-based therapies have the
potential to improve stroke outcomes. Methods—Eighteen patients with stable, chronic …

Introduction The therapeutic potential of mesenchymal stem cells (MSCs) for traumatic brain
injury (TBI) is attractive. Conducting systematic review and meta-analyses based on data …

OBJECTIVE The aim of this study was to evaluate the safety and clinical outcomes
associated with stereotactic surgical implantation of modified bone marrow–derived …

Background There is increasing evidence of therapeutic benefits from bone marrow (BM)-
derived mesenchymal stromal cells (MSC) in various animal models with neurologic …

Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the
brain due to an injury following a trauma, which can potentially cause severe physical …

Traumatic brain injury (TBI) represents physical damage to the brain tissue that induces
transitory or permanent neurological disabilities. TBI contributes to 50% of all trauma deaths …

Background Human neural stem cell implantation may offer improved recovery from stroke.
We investigated the feasibility of intracerebral implantation of the allogeneic human neural …

Objectives Evaluate the preclinical evidence for human cell therapies for the treatment of
traumatic brain injury (TBI), determine behavioral effect sizes for modified and non-modified …