Insomnia is a common disorder linked with adverse long-term medical and psychiatric
outcomes. The underlying pathophysiological processes and causal relationships of …

Chronic sleep disturbances, associated with cardiometabolic diseases, psychiatric disorders
and all-cause mortality,, affect 25–30% of adults worldwide. Although environmental factors …

Insomnia is the second most prevalent mental disorder, with no sufficient treatment
available. Despite substantial heritability, insight into the associated genes and …

Persistent insomnia is among the most frequent complaints in general practice. To identify
genetic factors for insomnia complaints, we performed a genome-wide association study …

Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies
have shown a heritable basis for various sleep-related traits, including insomnia, but robust …

Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated
with substantial functional deficits. Here, we identify 42 loci for self-reported daytime …

Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …

This review summarizes current research on the genetics of insomnia, as genetic
contributions are thought to be important for insomnia etiology. We begin by providing an …

CORRESPONDENCE of coronary artery disease, HF, and ischemic stroke as a whole, but
not AF (Figure). The associations remained in multivariable MR analyses with adjustment for …

Insomnia is reported to chronically affect 10∼ 15% of the adult population. However, very
little is known about the genetics and metabolism of insomnia. Here we surveyed 10,038 …