The nerve growth factor family of growth factors, collectively known as neurotrophins, are
evolutionarily ancient regulators with an enormous range of biological functions. Reflecting …

Neurotrophins are growth factors implicated in the development and maintenance of
different neuronal populations in the nervous system. Neurotrophins bind to two sets of …

Neurotrophins rely on Trk tyrosine kinase and p75 receptors for signal transduction.
Recently, other roles for these receptors have been identified. Many questions have been …

The neurotrophins, a class of four related growth factors, utilize a dual receptor system
consisting of Trk receptor tyrosine kinases and the structurally unrelated p75 NTR to …

The neurotrophins are growth factors that play critical roles in the development,
maintenance, survival, and death of the nervous system. The signal transducing systems …

Neurotrophins use two types of receptors, the Trk tyrosine kinase receptors and the p75
neurotrophin receptor (p75NTR), to regulate the growth, development, survival and repair of …

Neurotrophins are important regulators of embryonic development and adult function of most
populations of neurons in vertebrate nervous systems. This signaling system regulates many …

This review focuses on recent advances in our understanding of receptor-mediated
signaling by the neurotrophins NGF, BDNF, NT3, and NT4/5. Two distinct receptor types …

Neurotrophin signaling is essential for normal nervous system development and adult
function. Neurotrophins are secreted proteins that signal via interacting with two …

Target‐derived neurotrophins regulate neuronal survival and growth by interacting with cell‐
surface tyrosine kinase receptors. The p75 neurotrophin receptor (p75NTR) is coexpressed …