The mucosal and serological immune responses to the novel coronavirus (SARS-CoV-2) vaccines

RWY Chan, S Liu, JY Cheung, JGS Tsun… - Frontiers in …, 2021 - frontiersin.org
Background Although the serological antibody responses induced by SARS-CoV-2 vaccines
are well characterized, little is known about their ability to elicit mucosal immunity. Objectives …

Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination

J Tang, C Zeng, TM Cox, C Li, YM Son, IS Cheon… - Science …, 2022 - science.org
SARS-CoV-2 mRNA vaccination induces robust humoral and cellular immunity in the
circulation; however, it is currently unknown whether it elicits effective immune responses in …

A nasal vaccine with inactivated whole-virion elicits protective mucosal immunity against SARS-CoV-2 in mice

N Tokunoh, S Tamiya, M Watanabe… - Frontiers in …, 2023 - frontiersin.org
Introduction Vaccinations are ideal for reducing the severity of clinical manifestations and
secondary complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Antibody induction and immune response in nasal cavity by third dose of SARS-CoV-2 mRNA vaccination

A Ishizaka, M Koga, T Mizutani, R Uraki, S Yamayoshi… - Virology Journal, 2023 - Springer
Background The mucosa serves as the first defence against pathogens and facilitates the
surveillance and elimination of symbiotic bacteria by mucosal immunity. Recently, the mRNA …

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals

E Fraley, C LeMaster, E Geanes, D Banerjee, S Khanal… - BMC medicine, 2021 - Springer
Background The global pandemic of coronavirus disease 2019 (COVID-19) is caused by
infection with the SARS-CoV-2 virus. Currently, there are three approved vaccines against …

Characterization of SARS-CoV-2-Specific humoral and cellular immune responses induced by inactivated COVID-19 vaccines in a real-world setting

Z Li, T Xiang, B Liang, H Deng, H Wang… - Frontiers in …, 2021 - frontiersin.org
While the immunogenicity of inactivated vaccines against coronavirus disease 2019 (COVID‐
19) has been characterized in several well-conducted clinical trials, real-world evidence …

[HTML][HTML] Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva

TJ Ketas, D Chaturbhuj, VMC Portillo… - Pathogens and …, 2021 - ncbi.nlm.nih.gov
Abstract The approved Pfizer and Moderna mRNA vaccines are well known to induce serum
antibody responses to the SARS-CoV-2 Spike (S)-protein. However, their abilities to elicit …

Nasal and salivary mucosal humoral immune response elicited by mRNA BNT162b2 COVID-19 vaccine compared to SARS-CoV-2 natural infection

M Guerrieri, B Francavilla, D Fiorelli, M Nuccetelli… - Vaccines, 2021 - mdpi.com
SARS-CoV-2 antibody assays are crucial in managing the COVID-19 pandemic. Approved
mRNA COVID-19 vaccines are well known to induce a serum antibody responses against …

Mucosal immunity to severe acute respiratory syndrome coronavirus 2 infection

J Fröberg, DA Diavatopoulos - Current opinion in infectious …, 2021 - journals.lww.com
Although most clinical studies focus on antibodies and cellular immunity in peripheral blood,
mucosal immune responses in the respiratory tract play a key role in the early restriction of …

Distinct SARS-CoV-2 antibody reactivity patterns elicited by natural infection and mRNA vaccination

R Assis, A Jain, R Nakajima, A Jasinskas, S Khan… - npj Vaccines, 2021 - nature.com
We analyzed data from two ongoing COVID-19 longitudinal serological surveys in Orange
County, CA., between April 2020 and March 2021. A total of 8476 finger stick blood …