[HTML][HTML] Immune checkpoint inhibitors in triple negative breast cancer treatment: promising future prospects

R Thomas, G Al-Khadairi, J Decock - Frontiers in oncology, 2021 - frontiersin.org
Immunotherapy has emerged as the fifth pillar of cancer treatment alongside surgery,
radiotherapy, chemotherapy, and targeted therapy. Immune checkpoint inhibitors are the …

Checkpoint blockade strategies in the treatment of breast cancer: where we are and where we are heading

J Force, JHS Leal, HL McArthur - Current treatment options in oncology, 2019 - Springer
Opinion Statement Immunotherapy has become one of the greatest advances in medical
oncology over the last century; however, the optimal application for the treatment of breast …

The emerging role of immune checkpoint inhibitors in the treatment of triple-negative breast cancer

S Singh, A Numan, B Maddiboyina, S Arora, Y Riadi… - Drug discovery today, 2021 - Elsevier
Highlights•TNBCs is one of the most heterogenous form of breast cancer appear to have
elevated numbers of immune cells infiltration.•Using immune checkpoint inhibitors (ICIs) …

Role of immunotherapy in triple-negative breast cancer

TE Keenan, SM Tolaney - Journal of the National Comprehensive Cancer …, 2020 - jnccn.org
Immune checkpoint inhibitors (ICIs) have led to durable clinical remissions in many
metastatic cancers. However, the single-agent efficacy of ICIs in breast cancer is low …

[HTML][HTML] Immunotherapy in breast cancer: an overview of current strategies and perspectives

V Debien, A De Caluwé, X Wang… - NPJ Breast …, 2023 - nature.com
Recent progress in immunobiology has led the way to successful host immunity
enhancement against breast cancer. In triple-negative breast cancer, the combination of …

[HTML][HTML] Targeting immune checkpoints in breast cancer: an update of early results

C Solinas, A Gombos, S Latifyan, M Piccart-Gebhart… - ESMO open, 2017 - Elsevier
The immune tumour microenvironment has been shown to play a crucial role in the
development and progression of cancer. Expression of gene signatures, reflecting immune …

Checkpoint inhibitors in triple‐negative breast cancer (TNBC): Where to go from here

MJ Kwa, S Adams - Cancer, 2018 - Wiley Online Library
Advances in cancer immunotherapy and a growing body of research have focused on the
role of the antitumor response in breast cancer. Triple‐negative breast cancer (TNBC) is the …

Role of immunotherapy in breast cancer

SL Jacob, LA Huppert, HS Rugo - JCO Oncology Practice, 2023 - ascopubs.org
The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has
revolutionized the treatment of solid tumor malignancies. In breast cancer, the most robust …

[HTML][HTML] Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors

Y Abdou, A Goudarzi, JX Yu, S Upadhaya… - NPJ Breast …, 2022 - nature.com
The development of immunotherapy agents has revolutionized the field of oncology. The
only FDA-approved immunotherapeutic approach in breast cancer consists of immune …

New strategies in breast cancer: immunotherapy

L Pusztai, T Karn, A Safonov, MM Abu-Khalaf… - Clinical Cancer …, 2016 - AACR
More than 70% of breast cancers contain lymphocytic infiltration in the stroma, and
preclinical studies suggest that immunoediting and partial control of cancer progression by …