J Force, JHS Leal, HL McArthur - Current treatment options in oncology, 2019 - Springer
Opinion Statement Immunotherapy has become one of the greatest advances in medical oncology over the last century; however, the optimal application for the treatment of breast …
Highlights•TNBCs is one of the most heterogenous form of breast cancer appear to have elevated numbers of immune cells infiltration.•Using immune checkpoint inhibitors (ICIs) …
TE Keenan, SM Tolaney - Journal of the National Comprehensive Cancer …, 2020 - jnccn.org
Immune checkpoint inhibitors (ICIs) have led to durable clinical remissions in many metastatic cancers. However, the single-agent efficacy of ICIs in breast cancer is low …
V Debien, A De Caluwé, X Wang… - NPJ Breast …, 2023 - nature.com
Recent progress in immunobiology has led the way to successful host immunity enhancement against breast cancer. In triple-negative breast cancer, the combination of …
C Solinas, A Gombos, S Latifyan, M Piccart-Gebhart… - ESMO open, 2017 - Elsevier
The immune tumour microenvironment has been shown to play a crucial role in the development and progression of cancer. Expression of gene signatures, reflecting immune …
Advances in cancer immunotherapy and a growing body of research have focused on the role of the antitumor response in breast cancer. Triple‐negative breast cancer (TNBC) is the …
The advent of immunotherapy, particularly immune checkpoint inhibitors (ICIs), has revolutionized the treatment of solid tumor malignancies. In breast cancer, the most robust …
The development of immunotherapy agents has revolutionized the field of oncology. The only FDA-approved immunotherapeutic approach in breast cancer consists of immune …
L Pusztai, T Karn, A Safonov, MM Abu-Khalaf… - Clinical Cancer …, 2016 - AACR
More than 70% of breast cancers contain lymphocytic infiltration in the stroma, and preclinical studies suggest that immunoediting and partial control of cancer progression by …