Genome‐wide association study of schizophrenia in Ashkenazi Jews

FS Goes, J McGrath, D Avramopoulos… - American Journal of …, 2015 - Wiley Online Library
Schizophrenia is a common, clinically heterogeneous disorder associated with lifelong
morbidity and early mortality. Several genetic variants associated with schizophrenia have …

[HTML][HTML] Genome-wide association study of schizophrenia in Japanese population

K Yamada, Y Iwayama, E Hattori, K Iwamoto, T Toyota… - PloS one, 2011 - journals.plos.org
Schizophrenia is a devastating neuropsychiatric disorder with genetically complex traits.
Genetic variants should explain a considerable portion of the risk for schizophrenia, and …

Comparative genetic architectures of schizophrenia in East Asian and European populations

M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma… - Nature …, 2019 - nature.com
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …

Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia

SG Schwab, DB Wildenauer - European archives of psychiatry and clinical …, 2013 - Springer
The influence of genetic factors in the development of schizophrenia has been convincingly
demonstrated by family, twin, and adoption studies. The statistical construct of heritability is …

[HTML][HTML] Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry

TB Bigdeli, G Genovese, P Georgakopoulos… - Molecular …, 2020 - nature.com
Schizophrenia is a common, chronic and debilitating neuropsychiatric syndrome affecting
tens of millions of individuals worldwide. While rare genetic variants play a role in the …

[PDF][PDF] Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia

AC Need, JP McEvoy, M Gennarelli, EL Heinzen… - The American Journal of …, 2012 - cell.com
Schizophrenia is a severe psychiatric disorder with strong heritability and marked
heterogeneity in symptoms, course, and treatment response. There is strong interest in …

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

S Ripke, C O'dushlaine, K Chambert, JL Moran… - Nature …, 2013 - nature.com
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

Z Li, J Chen, H Yu, L He, Y Xu, D Zhang, Q Yi, C Li… - Nature …, 2017 - nature.com
We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese
individuals and performed further transancestry meta-analyses with data from the Psychiatry …

Uncovering the hidden risk architecture of the schizophrenias: confirmation in three independent genome-wide association studies

J Arnedo, DM Svrakic, C Del Val… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group
of heritable disorders caused by different genotypic networks that cause distinct clinical …

Genomewide association for schizophrenia in the CATIE study: results of stage 1

PF Sullivan, D Lin, JY Tzeng, E van den Oord… - Molecular …, 2008 - nature.com
Little is known for certain about the genetics of schizophrenia. The advent of genomewide
association has been widely anticipated as a promising means to identify reproducible DNA …