Role of IFN and complements system: innate immunity in SARS-CoV-2

T Shibabaw, MD Molla, B Teferi… - Journal of inflammation …, 2020 - Taylor & Francis
The critical role of the innate immune system has been confirmed in driving local and
systemic inflammation and the cytokine release storm in severe acute respiratory syndrome …

[HTML][HTML] Virus caused imbalance of type I IFN responses and inflammation in COVID-19

J Zhang, C Zhao, W Zhao - Frontiers in immunology, 2021 - frontiersin.org
The global expansion of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as one of the greatest …

[PDF][PDF] Innate immunity in COVID-19: Drivers of pathogenesis and potential therapeutic targets

V Ruenjaiman, N Hirankarn… - Asian Pacific journal of …, 2021 - apjai-journal.org
A novel severe acute respiratory syndrome COVID-19 caused by coronavirus SARS-CoV-2
has been confirmed to infect more than 100 million people globally, with mortality reaching …

SARS-CoV-2 infection and the antiviral innate immune response

H Yang, Y Lyu, F Hou - Journal of Molecular Cell Biology, 2020 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak began in
December 2019, causing the illness known as the novel coronavirus disease 2019 (COVID …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

Antagonism of type I interferon by severe acute respiratory syndrome coronavirus 2

H Xia, PY Shi - Journal of Interferon & Cytokine Research, 2020 - liebertpub.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), warranting urgent study of the molecular …

Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Mechanistic understanding of innate and adaptive immune responses in SARS-CoV-2 infection

MY Balkhi - Molecular Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have
triggered global pandemic that continue to impact adversely human health. New …

Innate immune response and inflammasome activation during SARS-CoV-2 infection

M Islamuddin, SA Mustfa, SNMN Ullah, U Omer, K Kato… - Inflammation, 2022 - Springer
The novel coronavirus SARS-CoV-2, responsible for the COVID-19 outbreak, has become a
pandemic threatening millions of lives worldwide. Recently, several vaccine candidates and …