The International Genetics of Ankylosing Spondylitis (IGAS) meeting was held in Houston,
Texas, July 25, 2009. Sixteen investigators from Asia, Australia, Europe, and North and …

Objective Several genetic risk variants for ankylosing spondylitis (AS) have been identified
in genome‐wide association studies. Our objective was to examine whether familial AS …

There is strong evidence from twin and family studies indicating that a substantial proportion
of the heritability of susceptibility to ankylosing spondylitis (AS) and its clinical manifestations …

Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the
axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes …

Objective. Ankylosing spondylitis (AS) is a debilitating chronic inflammatory condition with a
high degree of familiality (λ s= 82) and heritability (> 90%) that primarily affects spinal and …

Objective To assess the role of genes and the environment in determining the severity of
ankylosing spondylitis. Methods One hundred seventy‐three families with> 1 case of …

To address the 'missing heritability'and advance beyond GWA studies, a concerted effort
involving rethinking of study design and implementation of newer technologies will be …

Objective. A recent genome-wide association study has identified 2 single-nucleotide
polymorphisms (SNP) associated with ankylosing spondylitis (AS), rs10865331 (2p15) and …

Objective To identify genomic regions linked with determinants of age at symptom onset,
disease activity, and functional impairment in ankylosing spondylitis (AS). Methods A whole …

Ankylosing spondylitis (AS) is the prototypic form of axial spondyloarthritis (axSpA). It is
highly heritable, with studies conducted in twins and in unrelated cases and controls …