Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
Since the first textbook devoted to cytokine storm syndromes (CSSs) was published in 2019,
the world has changed dramatically and the term's visibility has broadened. Herein, we …

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis

LK Weaver, EM Behrens - Current treatment options in rheumatology, 2017 - Springer
Opinion statement Cytokine storm syndromes require rapid diagnosis and treatment to limit
the morbidity and mortality caused by the hyperinflammatory state that characterizes these …

The multifaceted immunology of cytokine storm syndrome

PY Lee, RQ Cron - The Journal of Immunology, 2023 - journals.aai.org
Cytokine storm syndromes (CSSs) are potentially fatal hyperinflammatory states that share
the underpinnings of persistent immune cell activation and uninhibited cytokine production …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …

[图书][B] Cytokine storm syndrome

RQ Cron, EM Behrens - 2019 - Springer
This textbook was necessitated by the broadening recognition of cytokine storm syndromes
(CSS) and their import and impact on health worldwide. We dedicate this to the clinicians …

Cytokine storm syndrome: looking toward the precision medicine era

EM Behrens, GA Koretzky - Arthritis & rheumatology, 2017 - Wiley Online Library
“Cytokine storm syndrome” is a diverse set of conditions unified by a clinical phenotype of
systemic inflammation, multi-organ failure, hyperferritinemia, and, if untreated, often death …

[HTML][HTML] Cytokine storm

DC Fajgenbaum, CH June - New England Journal of Medicine, 2020 - Mass Medical Soc
Cytokine Storm Cytokine storm, a life-threatening disorder involving cytokine elevations and
immune-cell hyperactivation, has various causes and is characterized by constitutional …

Cytokine storm syndrome

RQ Cron, G Goyal, WW Chatham - Annual Review of Medicine, 2023 - annualreviews.org
Cytokine storm syndrome (CSS), which is frequently fatal, has garnered increased attention
with the ongoing coronavirus pandemic. A variety of hyperinflammatory conditions …

Clinical features of cytokine storm syndrome

M Shimizu - Cytokine storm syndrome, 2019 - Springer
The common clinical features of cytokine storm syndrome (CSS) are sustained fever,
splenomegaly, hepatomegaly with liver dysfunction, lymphadenopathy, coagulopathy …

Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome

S Mahajan, CE Decker, Z Yang, D Veis, ED Mellins… - Journal of …, 2019 - Elsevier
Cytokine storm syndrome (CSS) is a life-threatening condition characterized by excessive
activation of T cells and uncontrolled inflammation, mostly described in patients with familial …