Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Abstract Interleukin-6 (IL-6) plays a crucial role in host defense against infection and tissue
injuries and is a bioindicator of multiple distinct types of cytokine storms. In this review, we …

The “cytokine storm”(CS) consists of a spectrum of different immune dysregulation disorders
characterized by constitutional symptoms, systemic inflammation and multiorgan dysfunction …

Background Multisystem inflammatory syndrome in children (MIS-C) is an acute, febrile,
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated syndrome …

Background: Churg-Strauss syndrome (CSS) is a rare, systemic, necrotizing vasculitis that
develops in some asthma patients. We previously reported that maintenance of the …

Background: Churg-Strauss syndrome (CSS) is a rare systemic necrotizing vasculitis that
develops in some asthma patients. However, it remains unknown what types of asthma …

Cytokine release syndrome (CRS) embodies a mixture of clinical manifestations, including
elevated circulating cytokine levels, acute systemic inflammatory symptoms and secondary …

BACKGROUND: Treatments for Churg-Strauss syndrome (CSS), a rare eosinophilic
vasculitis characterized by asthma, sinusitis, peripheral eosinophilia, pulmonary infiltrates …

Cytokine release syndrome (CRS) is a severe clinical syndrome marked by drastic elevation
of inflammatory cytokines such as interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF) …

Heterozygous missense mutations in coatomer protein subunit α, COPA, cause a syndrome
overlapping clinically with type I IFN-mediated disease due to gain-of-function in STING, a …