Background Multisystemic inflammatory syndrome in children (MIS-C) is a life-threatening
disease that occurs 2-5 weeks after severe acute respiratory syndrome coronavirus 2 …

The immunopathological hallmark of allergic diseases is elevated total and allergen specific
serum IgE levels along with inflammation. This inflammation results from the activation of a …

Objective: To determine the potential utility of cytokine and arachidonic acid metabolite
levels in ED patients with systemic inflammatory response syndrome (SIRS) as a predictor of …

Background We studied 2 unrelated patients with immune thrombocytopenia and
autoimmune hemolytic anemia in the setting of acute infections. One patient developed …

The cellular sensor stimulator of interferon genes (STING) initiates type I interferon (IFN) and
cytokine production following association with cyclic dinucleotides (CDNs) generated from …

The term inflammation is used to describe the localized tissue changes, including leukocyte
extravasation, that occur as part of the response to tissue damage, infection, or other …

Churg-Strauss syndrome (CSS) is a form of primary vasculitis characterized by allergy and
angiitis. In the organ systems involved (lung, heart, peripheral nervous system, and so forth) …

Mendelian autoinflammatory diseases characterized by constitutive activation of the type I
interferon pathway, the so-called type I interferonopathies, constitute a rapidly expanding …

Influenza virus is a significant pathogen in humans and animals with the ability to cause
extensive morbidity and mortality. Exuberant immune responses induced following infection …

Our current understanding of sepsis and multiple organ dysfunction needs to be revised, as
the uniformly negative results of new therapies for these disorders suggest. Previous …