Allenes are useful functional groups in synthesis as a result of their inherent chemical
properties and established reactivity patterns. One property of chemical bonding renders 1 …

Although chiral allene preparation via formal SN2'nucleophilic substitutions of
enantioenriched propargylic derivatives or metal-catalyzed reactions of racemic propargylic …

Asymmetric organocatalysis is a growing method for the synthesis of axially chiral
tetrasubstituted allenes, the most challenging one among allene syntheses. In this method …

Chiral allenes are readily accessed in a single pot operation in the reaction of terminal
alkynes, aldehydes, chiral secondary amines, and zinc halides in good yields (up to 77 …

The increasing synthetic utility of allenes in organic synthesis combined with their
incorporation into a growing list of natural products and active pharmaceutical ingredients …

The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral
starting materials remains a long-standing challenge in organic synthesis. Here, we report …

Allenes are molecules based on three carbons connected by two cumulated carbon–carbon
double bonds. Given their axially chiral nature and unique reactivity, substituted allenes …

Chiral allenes, which exist widely in natural products, bioactive pharmaceuticals, and
advanced functional materials, have received considerable attention from chemists. They …

The unique structural architecture of the orthogonal cumulative π-system in allenes has
garnered the attention of synthetic chemists for over a century. 1 From a general reactivity …

A one-pot synthesis of allenes by the 2-nitrobenzenesulfonylhydrazide-mediated coupling of
hydroxyaldehydes or ketones with alkynyl trifluoroborate salts is reported. This mild process …