Neuroinflammation in Alzheimer's disease: friend or foe?

C Scuderi, R Facchinetti, L Steardo… - The FASEB …, 2020 - Wiley Online Library
Neuroinflammation is part of the complex immune response within the central nervous
system (CNS), whose details have been partially elucidated. The CNS immune response …

Neuroinflammation, immune system and Alzheimer disease: searching for the missing link

F Guerriero, C Sgarlata, M Francis, N Maurizi… - Aging clinical and …, 2017 - Springer
Due to an increasingly aging population, Alzheimer disease (AD) represents a crucial issue
for the healthcare system because of its widespread prevalence and the burden of its care …

[HTML][HTML] Neuroinflammation, AD, and dementia

M Reale, T Brenner, NH Greig, N Inestrosa… - … Journal of Alzheimer's …, 2010 - ncbi.nlm.nih.gov
This special issue of the International Journal of Alzheimer's disease contains a series of
cuttingedge articles that deal with the broad issue of inflammatory and immunological …

Neuroinflammation in Alzheimer's disease: an understanding of physiology and pathology

M Obulesu, M Jhansilakshmi - International Journal of …, 2014 - Taylor & Francis
Alzheimer's disease (AD) is a devastative neurodegenerative disorder with complex
etiology. Neuroinflammation has been found to be an underlying cause of the disease …

Systemic and CNS inflammation crosstalk: implications for Alzheimer's disease

E Paouri, S Georgopoulos - Current Alzheimer Research, 2019 - ingentaconnect.com
After years of failed therapeutic attempts targeting beta-amyloid (Aβ) in AD, there is now
increasing evidence suggesting that inflammation holds a pivotal role in AD pathogenesis …

Inflammation in Alzheimer's disease

MT Heneka - Clinical Neuroscience Research, 2006 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disorder to date. Next to
its classical histopathological characteristics such as deposition of fibrillogenic amyloid β …

Evidence for neuroinflammation in Alzheimer's disease

A Walters, E Phillips, R Zheng, M Biju… - … in Neurology and …, 2016 - Wiley Online Library
New understanding in neuroscience has established that alongside the amyloid plaques,
neurofibrillary tangles and atrophy, the neuroinflammation triggered by the CNS's innate …

Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy

S Takeda, N Sato, R Morishita - Frontiers in aging neuroscience, 2014 - frontiersin.org
The incidence of dementia is increasing at an alarming rate, and has become a major public
health concern. Alzheimer disease (AD) is the most common form of dementia and is …

Neuroinflammation in Alzheimer's disease: insights from peripheral immune cells

Q Zhang, G Yang, Y Luo, L Jiang, H Chi, G Tian - Immunity & Ageing, 2024 - Springer
Alzheimer's disease (AD) is a serious brain disorder characterized by the presence of beta-
amyloid plaques, tau pathology, inflammation, neurodegeneration, and cerebrovascular …

[HTML][HTML] The roles of inflammation and immune mechanisms in Alzheimer's disease

LJ Van Eldik, MC Carrillo, PE Cole, D Feuerbach… - Alzheimer's & Dementia …, 2016 - Elsevier
Abstract The Alzheimer's Association's Research roundtable met in April 2015 to explore the
role of neuroinflammatory mechanisms in the progression of Alzheimer's disease (AD). The …