Genetic predisposition models to COVID-19 infection

F Darbeheshti, N Rezaei - Medical hypotheses, 2020 - ncbi.nlm.nih.gov
A wide range of disease severity among patients with coronavirus disease (COVID-19) has
attracted scientists' attention worldwide. Development of severe symptoms in some adults …

[HTML][HTML] The human genetic epidemiology of COVID-19

MEK Niemi, MJ Daly, A Ganna - Nature Reviews Genetics, 2022 - nature.com
Human genetics can inform the biology and epidemiology of coronavirus disease 2019
(COVID-19) by pinpointing causal mechanisms that explain why some individuals become …

[HTML][HTML] Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

[HTML][HTML] Genetic susceptibility to severe COVID-19

C Cappadona, V Rimoldi, EM Paraboschi… - Infection, Genetics and …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the
coronavirus disease 2019 (COVID-19) pandemic. Clinical manifestations of the disease …

Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] The genetic and evolutionary determinants of COVID-19 susceptibility

G Kerner, L Quintana-Murci - European Journal of Human Genetics, 2022 - nature.com
Devastating pandemics, such as that due to COVID-19, can provide strong testimony to our
knowledge of the genetic and evolutionary determinants of infectious disease susceptibility …

Post-Mendelian genetic model in COVID-19

N Picchiotti, E Benetti, C Fallerini, S Daga… - medRxiv, 2021 - medrxiv.org
Host genetics is an emerging theme in COVID-19 and few common polymorphisms and
some rare variants have been identified, either by GWAS or candidate gene approach …

[HTML][HTML] Presence of rare potential pathogenic variants in subjects under 65 years old with very severe or fatal COVID-19

R López-Rodríguez, M Del Pozo-Valero, M Corton… - Scientific reports, 2022 - nature.com
Rare variants affecting host defense against pathogens could be involved in COVID-19
severity and may help explain fatal outcomes in young and middle-aged patients. Our aim …

[HTML][HTML] Host genetic factors determining COVID-19 susceptibility and severity

TP Velavan, SR Pallerla, J Rüter, Y Augustin… - …, 2021 - thelancet.com
The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections …

[HTML][HTML] Targeted screening of genetic associations with COVID-19 susceptibility and severity

P Li, Y Ke, W Shen, S Shi, Y Wang, K Lin, X Guo… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 pandemic has resulted in great morbidity and mortality worldwide and
human genetic factors have been implicated in the susceptibility and severity of COVID-19 …