[HTML][HTML] Crucial mutations of spike protein on SARS-CoV-2 evolved to variant strains escaping neutralization of convalescent plasmas and RBD-specific monoclonal …

C Ding, J He, X Zhang, C Jiang, Y Sun… - Frontiers in …, 2021 - frontiersin.org
Small number of SARS-CoV-2 epidemic lineages did not efficiently exhibit a neutralization
profile, while single amino acid mutation in the spike protein has not been confirmed in …

[HTML][HTML] Emerging SARS-CoV-2 variants reduce neutralization sensitivity to convalescent sera and monoclonal antibodies

J Hu, P Peng, K Wang, L Fang, F Luo, A Jin… - Cellular & molecular …, 2021 - nature.com
Coronaviruses are enveloped, positive-stranded RNA viruses that contain the largest known
RNA genomes to date. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[HTML][HTML] Infection-and vaccine-induced antibody binding and neutralization of the B. 1.351 SARS-CoV-2 variant

VV Edara, C Norwood, K Floyd, L Lai… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising
concerns about the efficacy of infection-or vaccine-induced antibodies. We compared …

[HTML][HTML] Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals

EC Chen, P Gilchuk, SJ Zost, N Suryadevara… - Cell Reports, 2021 - cell.com
Unrelated individuals can produce genetically similar clones of antibodies, known as public
clonotypes, which have been seen in responses to different infectious diseases, as well as …

A high-throughput cell-and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma

C Fenwick, P Turelli, C Pellaton, A Farina… - Science Translational …, 2021 - science.org
The detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific
antibodies in the serum of an individual indicates previous infection or vaccination …

The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - MedRxiv, 2021 - medrxiv.org
One year in the coronavirus disease 2019 (COVID-19) pandemic, the first vaccines are
being rolled out under emergency use authorizations. It is of great concern that newly …

[HTML][HTML] The effect of spike mutations on SARS-CoV-2 neutralization

C Rees-Spear, L Muir, SA Griffith, J Heaney, Y Aldon… - Cell reports, 2021 - cell.com
Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines show
protective efficacy, which is most likely mediated by neutralizing antibodies recognizing the …

Cross-neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike

S Changrob, Y Fu, JJ Guthmiller, PJ Halfmann, L Li… - Mbio, 2021 - Am Soc Microbiol
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have
arisen that exhibit increased viral transmissibility and partial evasion of immunity induced by …

[HTML][HTML] SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera

A Kuzmina, Y Khalaila, O Voloshin, A Keren-Naus… - Cell host & …, 2021 - cell.com
Toward eradicating the COVID-19 pandemic, vaccines that induce high humoral and cellular
immune responses are essential. However, SARS-CoV-2 variants have begun to emerge …

SARS-CoV-2 spike E156G/Δ157-158 mutations contribute to increased infectivity and immune escape

T Mishra, R Dalavi, G Joshi, A Kumar… - Life Science …, 2022 - life-science-alliance.org
Breakthrough infections by emerging SARS-CoV-2 variants raise significant concerns. Here,
we sequence-characterized the spike gene from breakthrough infections that corresponded …