Objective Apelin is a novel adipokine acting on APJ receptor, regulated by insulin and tumor
necrosis factor-α (TNF-α) in adipose tissue (AT). Plasma apelin levels are increased in …

Objective: Apelin is an adipokine which plays a role in the regulation of glucose
homeostasis and may contribute to the link between increased adipose tissue mass and …

The results presented herein demonstrate that apelin is expressed and secreted by both
human and mouse adipocytes. Apelin mRNA levels in isolated adipocytes are close to other …

Apelin, an adipocyte-secreted factor upregulated by insulin, is increased in adipose tissue
(AT) and plasma with obesity. Apelin was recently identified as a new player in the control of …

Apelin is a peptide present in different cell types and secreted by adipocytes in humans and
rodents. Apelin exerts its effects through a G-protein-coupled receptor called APJ. During the …

Objective (s) Apelin is novel adipokine acting on APJ receptor, regulated by insulin and
tumor necrosis factor-alpha (TNF-alpha). Plasma apelin levels are increased in obese …

Background: Apelin is a novel adipocytokine produced by white adipose tissue that binds
the APJ receptor with high affinity. Insulin may have a role in regulation of apelin synthesis …

Apelin is a peptide known as the ligand of the G-protein-coupled receptor APJ. Several
active apelin forms exist such as apelin-36, apelin-17, apelin-13, and the pyroglutamated …

We have recently identified apelin as a novel adipokine up‐regulated by insulin and obesity.
Since obesity and insulin resistance are associated with chronically elevated levels of both …

It has been reported that apelin functions as an adipokine, which has been associated to
obesity and insulin resistance. The objective of this study was to analyze the apelin mRNA …