The integrins have been grouped into three subfamilies based on the utilization of three
distinct beta chain subunits, β1, β2 and β3. The recent discovery of β4 and β5 subunits, and …

To study the differential expression of the murine VLA-4 (α4β1) integrin, the 5′-flanking
region of the gene for the α subunit (α4m) was isolated and a cDNA for α4m was obtained …

The structure‐function relationship of the human integrin VLA‐4 (α4/β1; CD49d/CD29), has
been studied in the human B‐cell line Ramos by immunochemical and functional analysis …

Integrins are a superfamily of alpha beta heterodimers, most of which serve as cell surface
receptors for extracellular matrix proteins. In this report, we demonstrate that the recently …

A single-chain antibody construct was prepared containing the VH and VL regions of anti-
(integrin α4) antibody HP1/2, an interchain linker and a KDEL endoplasmic reticulum …

We have investigated the regulation by divalent cations Mg 2+, Ca 2+ and Mn 2+ of the
functional activity of the human integrin VLA-1 expressed on neuroblastoma NB100 cells …

A characteristic feature of integrin–ligand interactions is the requirement for divalent cations.
Putative cation binding sites have been identified in the α and β subunit of the α4 integrins …

On platelets and other cell types, VLA-6 is a typical integrin heterodimer, with α 6-β 1 subunit
association. However, on colon carcinoma cell lines and other epithelial cells the α 6 subunit …

To assess directly the functional role of the integrin VLA-3 (alpha 3 beta 1), we transfected
human alpha 3 cDNA into erythroleukemia (K562) cells and rhabdomyosarcoma (RD) cells …

Abstract Very‐late antigen (VLA)‐4 (CD49d/CD29) constitutes the only member of the β1
integrin family that plays a role in the interaction of lymphoid cells with both extracellular …