The integrin VLA-4 (α4β1) is a receptor for fibronectin and vascular cell-adhesion molecule
1 (VCAM-1). Four functionally different epitopes, designated A, B1, B2 and C, have …

α 4 β 1 integrin (VLA-4) appears to be unique among the leukocyte integrins in that it can
initiate the adhesion of circulating lymphocytes without cellular activation. It is not known …

Modulation of VLA integrins was studied in several human T cell clones upon specific and
nonspecific cellular activation. Human activated T lymphocytes down-regulated both alpha 4 …

We examined the expression of VLA-5, a libronectin receptor, during human B cell
development and activation. VLA-5 is a member of the integrin supergene family; VLAs arc …

Monoclonal antibodies (mAbs) have been produced against the chicken beta 1 subunit that
affect integrin functions, including ligand binding, alpha subunit association, and regulation …

We have generated a panel of potent, selective monoclonal antibodies that bind human and
mouse α v β 6 integrin with high affinity (up to 15 pm). A subset of these antibodies blocked …

The VLA-4 (CD49d/CD29) integrin is the only member of the VLA family expressed by
resting lymphoid cells that has been involved in cell-cell adhesive interactions. We here …

A stabilization of both the precursor and the mature β1 integrin subunit was observed in
metabolically labeled human skin fibroblasts and Molt‐4 T lymphocytes upon addition of …

Selected functions of integrins, including regulated cytoskeletal association and
transmembrane signaling, depend on a poorly defined bidirectional communication …

The integrin VLA-3 is a cell surface receptor, which binds to fibronectin, laminin, collagen
type I and VI (Takada, Y., EA Wayner, WG Carter, and ME Hemler. 1988. J. Cell. Biochem …