The dynamics of the actin cytoskeleton and its regulation by Rho GTPases are essential to
maintain cell shape, to allow cell motility and are also critical during cell cycle progression …

Members of the Rho family of small GTPases are crucial regulators of biological responses
in eukaryotic cells, including cytoskeletal dynamics, cell motility and cell cycle progression …

The past year has produced an abundance of data on the function and regulation of Rho-
related GTP-binding proteins. In mammalian cells, it has been shown that Rho is required for …

Animal cell division is a fundamental process that requires complex changes in cytoskeletal
organization and function. Aberrant cell division often has disastrous consequences for the …

The importance for the Rho GTPases Rho, Rac, and Cdc42 for the heterogeneity of the actin
cytoskeleton is well documented. However, there is now an emerging view that they also …

Rho GTPases regulate a diverse range of cellular functions primarily through their ability to
modulate microtubule dynamics and the actin-myosin cytoskeleton. Both of these …

Rho GTPases are molecular switches that regulate many essential cellular processes,
including actin dynamics, gene transcription, cell-cycle progression and cell adhesion …

Until recently, members of the Rho family of GTPases were considered primarily to be
regulators of the distinct structures making up the actin cytoskeleton. Several Rho GTPases …

Rho GTPases regulate cytoskeletal and cell adhesion dynamics and thereby coordinate a
wide range of cellular processes, including cell migration, cell polarity and cell cycle …

Rho GTPases are key regulators of cytoskeletal dynamics and affect many cellular
processes, including cell polarity, migration, vesicle trafficking and cytokinesis. These …