OBJECTIVES: Inflammatory bowel diseases (IBD)—Crohn's disease (CD) and ulcerative
colitis (UC)—are chronic gastrointestinal inflammatory disorders with a complex genetic …

Background A German genome-wide nonsynonymous single nucleotide polymorphism
(nsSNP) association study identified ATG16L1 as a Crohn's disease (CD) susceptibility …

Background Crohn's disease (CD) has the highest prevalence among individuals of
Ashkenazi Jewish (AJ) descent compared to non-Jewish Caucasian populations (NJ). We …

Background & Aims Recent studies reported a role for more than 70 genes or loci in the
susceptibility to Crohn's disease (CD). However, the impact of these associations in clinical …

Inflammatory bowel disease (IBD) typically manifests as either ulcerative colitis (UC) or
Crohn's disease (CD). Systematic identification of susceptibility genes for IBD has thus far …

Abstract Background and Aims The inflammatory bowel diseases (IBDs) Crohn's disease
(CD) and ulcerative colitis are complex disorders with an important genetic determinant. One …

Crohn disease (CD), a sub-entity of inflammatory bowel disease (IBD), is a complex
polygenic disorder. Although recent studies have successfully identified CD-associated …

OBJECTIVE Recently, separate genome-wide association analyses have identified
nonsynonymous SNPs in IL23R and ATG16L1 (rs11209026; c1142G> A, R381Q, and …

Background Crohn's disease (CD) and ulcerative colitis (UC), 2 major forms of inflammatory
bowel disease (IBD), are complex disorders with significant genetic predisposition. The first …

Background Both ulcerative colitis (UC) and Crohn's disease (CD) have a complex etiology
involving multiple genetic and environmental factors. Many genome-wide association …