A single residue in Ebola virus receptor NPC1 influences cellular host range in reptiles
Filoviruses are the causative agents of an increasing number of disease outbreaks in human
populations, including the current unprecedented Ebola virus disease (EVD) outbreak in …
populations, including the current unprecedented Ebola virus disease (EVD) outbreak in …
Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression
V Wahl-Jensen, S Kurz, F Feldmann… - PLoS neglected …, 2011 - journals.plos.org
Zaire ebolavirus (ZEBOV) infections are associated with high lethality in primates. ZEBOV
primarily targets mononuclear phagocytes, which are activated upon infection and secrete …
primarily targets mononuclear phagocytes, which are activated upon infection and secrete …
Characterization of Ebolavirus regulatory genomic regions
G Neumann, S Watanabe, Y Kawaoka - Virus Research, 2009 - Elsevier
For filoviruses, such as Ebolavirus and the closely related Marburgvirus, transcriptional
regulation is poorly understood. The open reading frames (ORFs) that encode the viral …
regulation is poorly understood. The open reading frames (ORFs) that encode the viral …
[图书][B] Marburg and Ebola viruses
HD Klenk, W Slenczka, H Feldmann - 1999 - Springer
Marburg and Ebola virus, the two species within the family Filoviridae, are among the most
pathogenic agents causing fulminant hemorrhagic fever in humans and nonhuman …
pathogenic agents causing fulminant hemorrhagic fever in humans and nonhuman …
The Ebola Virus Glycoprotein Contributes to but Is Not Sufficient for Virulence In Vivo
Among the Ebola viruses most species cause severe hemorrhagic fever in humans;
however, Reston ebolavirus (REBOV) has not been associated with human disease despite …
however, Reston ebolavirus (REBOV) has not been associated with human disease despite …
Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen
KB Spurgers, T Alefantis, BD Peyser, GT Ruthel… - Molecular & Cellular …, 2010 - ASBMB
An assessment of the total protein composition of filovirus (ebolavirus and marburgvirus)
virions is currently lacking. In this study, liquid chromatography-linked tandem mass …
virions is currently lacking. In this study, liquid chromatography-linked tandem mass …
In vivo Ebola virus infection leads to a strong innate response in circulating immune cells
Background Ebola virus is the causative agent of a severe syndrome in humans with a
fatality rate that can approach 90%. During infection, the host immune response is thought to …
fatality rate that can approach 90%. During infection, the host immune response is thought to …
Early transcriptional changes within liver, adrenal gland, and lymphoid tissues significantly contribute to ebola virus pathogenesis in cynomolgus macaques
Ebola virus (EBOV) continues to pose a significant threat to human health, as evidenced by
the 2013–2016 epidemic in West Africa and the ongoing outbreak in the Democratic …
the 2013–2016 epidemic in West Africa and the ongoing outbreak in the Democratic …
[HTML][HTML] Innate immune evasion by filoviruses
CF Basler - Virology, 2015 - Elsevier
Ebola viruses and Marburg viruses, members of the filovirus family, cause severe
hemorrhagic fever. The ability of these viruses to potently counteract host innate immune …
hemorrhagic fever. The ability of these viruses to potently counteract host innate immune …
Ebola virus: the search for vaccines and treatments
JA Wilson, CM Bosio, MK Hart - Cellular and Molecular Life Sciences …, 2001 - Springer
Ebola viruses belong to the family Filoviridae, which are among the most virulent infectious
agents known. These viruses cause acute, and frequently fatal, hemorrhagic fever in …
agents known. These viruses cause acute, and frequently fatal, hemorrhagic fever in …