Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high
fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic …

Dysregulated host immune responses: can we alter the outcome? As with other viral
infections, initial induction of type 1 IFNs are likely to elicit subsequent productive immune …

Viruses of the genera Ebolavirus and Marburgvirus are filoviruses that cause haemorrhagic
fever in primates, with extremely high fatality rates. Studies have focused on elucidating how …

The Filoviruses Marburg virus and Ebola virus are among the deadliest of human
pathogens, causing fulminant hemorrhagic fevers typified by overmatched specific immune …

The filoviruses, Ebola virus (EBOV) and Marburg virus (MARV), are highly lethal zoonotic
agents of concern as emerging pathogens and potential bioweapons. Antigen-presenting …

Ebola virus (EBOV) is a negative single-stranded RNA virus within the Filoviridae family and
the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including …

The filoviruses Ebola and Marburg are zoonotic agents that are classified as both biosafety
level 4 and category A list pathogens. These viruses are pathogenic in humans and cause …

Ebola viruses and Marburg viruses include some of the most virulent and fatal pathogens
known to humans. These viruses cause severe haemorrhagic fevers, with case fatality rates …

© 2014 Macmillan Publishers Limited. All rights reserved safely studied. Scientists have
learned how these viruses work and have created the first experimental vaccines and …

Infections with filoviruses in humans are highly virulent, causing hemorrhagic fevers which
result in up to 90% mortality. In addition to natural infections, the ability to use these viruses …