[HTML][HTML] The serum metabolome of moderate and severe COVID-19 patients reflects possible liver alterations involving carbon and nitrogen metabolism

M Caterino, M Costanzo, R Fedele, A Cevenini… - International Journal of …, 2021 - mdpi.com
COVID-19 is a global threat that has spread since the end of 2019, causing severe clinical
sequelae and deaths, in the context of a world pandemic. The infection of the highly …

[HTML][HTML] Metabolomics markers of COVID-19 are dependent on collection wave

HM Lewis, Y Liu, CF Frampas, K Longman, M Spick… - Metabolites, 2022 - mdpi.com
The effect of COVID-19 infection on the human metabolome has been widely reported, but to
date all such studies have focused on a single wave of infection. COVID-19 has generated …

[HTML][HTML] Metabolic signatures associated with severity in hospitalized COVID-19 patients

J Marín-Corral, J Rodríguez-Morató… - International journal of …, 2021 - mdpi.com
The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the
metabolic pathways that are altered early with viral infection and their association with …

[HTML][HTML] Metabolomics study of COVID-19 patients in four different clinical stages

A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …

[HTML][HTML] The specific metabolome profiling of patients infected by SARS-COV-2 supports the key role of tryptophan-nicotinamide pathway and cytosine metabolism

H Blasco, C Bessy, L Plantier, A Lefevre, E Piver… - Scientific reports, 2020 - nature.com
The biological mechanisms involved in SARS-CoV-2 infection are only partially understood.
Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search …

[PDF][PDF] Plasma metabolomic and lipidomic alterations associated with COVID-19

D Wu, T Shu, X Yang, JX Song, M Zhang… - National Science …, 2020 - academic.oup.com
The pandemic of the coronavirus disease 2019 (COVID-19) has become a global public
health crisis. The symptoms of COVID-19 range from mild to severe, but the physiological …

[PDF][PDF] SARS-CoV-2 infection dysregulates the metabolomic and lipidomic profiles of serum

C Bruzzone, M Bizkarguenaga, R Gil-Redondo… - Iscience, 2020 - cell.com
COVID-19 is a systemic infection that exerts significant impact on the metabolism. Yet, there
is little information on how SARS-CoV-2 affects metabolism. Using NMR spectroscopy, we …

The serum metabolome of COVID-19 patients is distinctive and predictive

D Shi, R Yan, L Lv, H Jiang, Y Lu, J Sheng, J Xie, W Wu… - Metabolism, 2021 - Elsevier
Background Metabolism is critical for sustaining life, immunity and infection, but its role in
COVID-19 is not fully understood. Methods Seventy-nine COVID-19 patients, 78 healthy …

Metabolomic analyses reveal new stage-specific features of COVID-19

H Jia, C Liu, D Li, Q Huang, D Liu… - European …, 2022 - Eur Respiratory Soc
The current pandemic of coronavirus disease 2019 (COVID-19) has affected> 160 million
individuals to date, and has caused millions of deaths worldwide, at least in part due to the …

[HTML][HTML] Plasma metabolomics and gene regulatory networks analysis reveal the role of nonstructural SARS-CoV-2 viral proteins in metabolic dysregulation in COVID …

VA Ivanisenko, EV Gaisler, NV Basov, AD Rogachev… - Scientific Reports, 2022 - nature.com
Metabolomic analysis of blood plasma samples from COVID-19 patients is a promising
approach allowing for the evaluation of disease progression. We performed the …