Cell transplantation for Parkinson's disease: present status

R Drucker-Colín, L Verdugo-Díaz - Cellular and molecular neurobiology, 2004 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of neurons in
the substantia nigra pars compacta and a striatal deficiency of dopamine. PD typically affects …

Cell transplantation for Parkinson's disease

B Roitberg, K Urbaniak, M Emborg - Neurological research, 2004 - Taylor & Francis
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
degeneration of the dopamine producing neurons projecting from the substantia nigra into …

Cell therapy for Parkinson's disease: problems and prospects

A Björklund - Stem Cells: Nuclear Reprogramming and …, 2005 - Wiley Online Library
Cell replacement therapy in Parkinson's disease (PD) has so far been based on the use of
primary dopaminergic (DA) neuroblasts obtained from the brain of aborted human fetuses …

Stem cell‐based therapy for Parkinson's disease

AS Correia, SV Anisimov, JY Li, P Brundin - Annals of Medicine, 2005 - Taylor & Francis
Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Neural stem cells and transplantation studies in Parkinson's disease

R Pardal, J López-Barneo - Stem cell transplantation, 2012 - Springer
Abstract Parkinson's disease (PD), one of the most frequent neurodegenerative disorders, is
primarily caused by the selective degeneration of specific neuronal populations, particularly …

Stem cell transplantation: a promising therapy for Parkinson's disease

Y Wang, S Chen, D Yang, W Le - Journal of neuroimmune pharmacology, 2007 - Springer
Parkinson's disease is one of the most common neurodegenerative diseases caused by the
loss of dopaminergic neurons in the substantia nigra pars compacta. Pharmacological …

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease

O Lindvall, Z Kokaia - Trends in Pharmacological sciences, 2009 - cell.com
In Parkinson's disease (PD), the main pathology is a loss of nigrostriatal dopamine (DA)
neurons. Clinical trials with intrastriatal transplantation of human embryonic mesencephalic …

Stem cell therapy for Parkinson's disease: where do we stand?

L Roybon, NS Christophersen, P Brundin, JY Li - Cell and tissue research, 2004 - Springer
A major neuropathological feature of Parkinson's disease (PD) is the loss of nigrostriatal
dopaminergic neuron. Patients exhibit motor symptoms, including bradykinesia, rigidity, and …

Stem cells for cell therapy in Parkinson's disease

O Lindvall - Pharmacological research, 2003 - Elsevier
Clinical studies with intrastriatal transplants of human embryonic mesencephalic tissue have
provided proof-of-principle for the cell replacement strategy in Parkinson's disease (PD) …

Cell-based therapies for Parkinson's disease

SC Dyson, RA Barker - Expert Review of Neurotherapeutics, 2011 - Taylor & Francis
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide, classically characterized by a triad of motor features: bradykinesia, rigidity and …