Pathophysiology and potential therapeutic candidates for COVID-19: a poorly understood arena

A Samaddar, M Grover, VL Nag - Frontiers in pharmacology, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19), an acute onset pneumonia caused by a novel
Betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged …

Pharmacological insight into potential therapeutic agents for the deadly Covid-19 pandemic

R Bhandari, G Khanna, A Kuhad - European Journal of Pharmacology, 2021 - Elsevier
Coronaviruses are pleomorphic, enveloped, or spherical viruses, which have a size ranging
from 80 to 120 nm. These viruses act on receptors that cause the triggering of fusion …

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

An overview on anti-COVID-19 drug achievements and challenges ahead

M Valipour, H Irannejad, H Keyvani - ACS Pharmacology & …, 2023 - ACS Publications
The appearance of several coronavirus pandemics/epidemics during the last two decades
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …

Current and future therapeutical approaches for COVID-19

Y Duan, Y Yao, SA Kumar, HL Zhu, J Chang - Drug Discovery Today, 2020 - Elsevier
Coronavirus 2019 (COVID-19), the WHO-classified novel coronavirus of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly become a global pandemic …

Mechanism of action of small-molecule agents in ongoing clinical trials for SARS-CoV-2: a review

L Zhao, S Li, W Zhong - Frontiers in Pharmacology, 2022 - frontiersin.org
Since the first reports from December 2019, COVID-19 caused an overwhelming global
pandemic that has affected 223 countries, seriously endangering public health and creating …

[PDF][PDF] Distinctive Therapeutic Strategies against Corona Virus19 (COVID-19): A Pharmacological Review.

YA Nomier, DS Rao, AH Suhaqi… - Systematic Reviews in …, 2020 - researchgate.net
Coronaviruses (CoVs) are RNA viruses threatened the global health. The causative
microorganism, causing coronavirus disease-2019 (COVID-19), is known as (novel …

[PDF][PDF] Emergence, transmission, and potential therapeutic targets for the COVID-19 pandemic associated with the SARS-CoV-2

AM Patil, JR Göthert, V Khairnar - Cellul Physiol Biochem Int J Exp …, 2020 - researchgate.net
The pandemic of the severe acute respiratory syndrome coronavirus (SARS-CoV)-2 at the
end of 2019 marked the third outbreak of a highly pathogenic coronavirus affecting the …

What are the current anti-COVID-19 drugs? From traditional to smart molecular mechanisms

S Aboul-Fotouh, AN Mahmoud, EM Elnahas, MZ Habib… - Virology journal, 2023 - Springer
Abstract Background Coronavirus disease 19 (COVID-19) is the disease caused by SARS-
CoV-2, a highly infectious member of the coronavirus family, which emerged in December …

Current therapies under investigation for COVID-19: Potential COVID-19 treatments

E Weisberg, M Sattler, PL Yang… - Canadian Journal of …, 2020 - cdnsciencepub.com
In response to the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), researchers are expeditiously searching for antiviral treatments able to alleviate the …