Post-translational histone modifications and linker histone incorporation regulate chromatin
structure and genome activity. How these systems interface on a molecular level is unclear …

The tails of histone proteins are central players for all chromatin-mediated processes.
Whereas the N-terminal histone tails have been studied extensively, little is known about the …

Post-translational modifications of histones regulate all DNA-templated processes, including
replication, transcription and repair. These modifications function as platforms for the …

Post-translational modifications of proteins have emerged as a major mechanism for
regulating gene expression. However, our understanding of how histone modifications …

H1 linker histones are highly abundant proteins that compact nucleosomes and chromatin to
regulate DNA accessibility and transcription. However, the mechanisms that target H1 …

Nucleosome arrays undergo salt-dependent self-association into large oligomers in a
process thought to recapitulate essential aspects of higher-order tertiary chromatin structure …

The structural unit of eukaryotic chromatin is a nucleosome, comprising two histone H2A-
H2B heterodimers and one histone (H3-H4) 2 tetramer, wrapped around by∼ 146 bp of …

The structural unit of eukaryotic chromatin is a nucleosome, comprising two histone
H2A/H2B heterodimers and one histone (H3/H4) 2 tetramer, wrapped around by∼ 146-bp …

Histones have two structurally and functionally distinct domains: globular domains forming
the nucleosomal core around which DNA is wrapped and unstructured tails protruding from …

Förster resonance energy transfer was used to monitor the dynamic conformations of
mononucleosomes under different chromatin folding conditions to elucidate the role of the …