Fc-independent protection from SARS-CoV-2 infection by recombinant human monoclonal antibodies
T Noy-Porat, A Edri, R Alcalay, E Makdasi, D Gur… - Antibodies, 2021 - mdpi.com
The use of passively-administered neutralizing antibodies is a promising approach for the
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
prevention and treatment of SARS-CoV-2 infection. Antibody-mediated protection may …
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
Emerging evidence indicates that both neutralizing and Fc-mediated effector functions of
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
SARS-CoV-2 monoclonal antibodies with therapeutic potential: Broad neutralizing activity and No evidence of antibody-dependent enhancement
YT Wang, RD Allen III, K Kim, N Shafee, AJ Gonzalez… - Antiviral research, 2021 - Elsevier
Monoclonal antibodies (mAbs) are emerging as safe and effective therapeutics against
SARS-CoV-2. However, variant strains of SARS-CoV-2 have evolved, with early studies …
SARS-CoV-2. However, variant strains of SARS-CoV-2 have evolved, with early studies …
A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques
Background Human monoclonal antibody (mAb) treatments are promising for COVID-19
prevention or therapy. The pre-exposure prophylactic efficacy of neutralizing antibodies that …
prevention or therapy. The pre-exposure prophylactic efficacy of neutralizing antibodies that …
The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants
E Makdasi, A Zvi, R Alcalay, T Noy-Porat, E Peretz… - Cell Reports, 2021 - cell.com
A wide range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
neutralizing monoclonal antibodies (mAbs) have been reported, most of which target the …
neutralizing monoclonal antibodies (mAbs) have been reported, most of which target the …
Review of therapeutic mechanisms and applications based on SARS-CoV-2 neutralizing antibodies
COVID-19 pandemic is a global public health emergency. Despite extensive research, there
are still few effective treatment options available today. Neutralizing-antibody-based …
are still few effective treatment options available today. Neutralizing-antibody-based …
The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates
Summary SARS-CoV-2 neutralizing antibodies (NAbs) protect against COVID-19, making
them a focus of vaccine design. A safety concern regarding SARS-CoV-2 antibodies is …
them a focus of vaccine design. A safety concern regarding SARS-CoV-2 antibodies is …
Neutralizing Antibodies in the Prevention and Treatment of COVID-19
RR Razonable, P Chen - Frontiers in immunology, 2022 - frontiersin.org
The COVID-19 therapeutic landscape rapidly evolved throughout the course of the SARS-
CoV-2 pandemic. However, the ingenuity of our community quickly coalesced to identify …
CoV-2 pandemic. However, the ingenuity of our community quickly coalesced to identify …
Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective
Y Huang, H Sun, H Yu, S Li, Q Zheng… - Antibody …, 2020 - academic.oup.com
The rapid emergence of Coronavirus disease-2019 (COVID-19) caused by severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2) as a pandemic that presents an urgent …
respiratory syndrome 2 coronavirus (SARS-CoV-2) as a pandemic that presents an urgent …