Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder

DE Dickel, J Veenstra-VanderWeele… - Archives of general …, 2006 - jamanetwork.com
Context The first 2 independent linkage studies for obsessive-compulsive disorder (OCD)
identified a region on 9p24 with suggestive evidence for linkage. The glutamate transporter …

A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder

JR Wendland, PR Moya, KR Timpano… - Archives of general …, 2009 - jamanetwork.com
Context Recent evidence from linkage analyses and follow-up candidate gene studies
supports the involvement ofSLC1A1, which encodes the neuronal glutamate transporter, in …

Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder

J Veenstra-VanderWeele, SJ Kim, D Gonen… - Molecular …, 2001 - nature.com
The first genome scan conducted in early-onset obsessive-compulsive disorder used a non-
parametric analysis to identify a peak in a region of chromosome 9 containing the gene …

Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder

PD Arnold, T Sicard, E Burroughs… - Archives of general …, 2006 - jamanetwork.com
Context There is strong evidence from family and twin studies that genetic determinants play
an important role in the etiology of obsessive-compulsive disorder (OCD). In the only …

Association of the SLC1A1 glutamate transporter gene and obsessive‐compulsive disorder

SE Stewart, JA Fagerness, J Platko… - American Journal of …, 2007 - Wiley Online Library
Abstract Context: Obsessive‐Compulsive Disorder (OCD) is a debilitating illness with
putative glutamatergic abnormalities. Two separate proximal haplotypes in the glutamate …

Comprehensive family‐based association study of the glutamate transporter gene SLC1A1 in obsessive‐compulsive disorder

J Samuels, Y Wang, MA Riddle… - American Journal of …, 2011 - Wiley Online Library
SLC1A1 is a neuronal gluamate transporter genes and is a promising candidate gene for
obsessive-compulsive disorder (OCD)[Leckman and Kim, 2006]. This gene is expressed in …

A family‐based association study of the glutamate transporter gene SLC1A1 in obsessive–compulsive disorder in 378 families

YY Shugart, Y Wang, JF Samuels… - American Journal of …, 2009 - Wiley Online Library
SLC1A encodes the neuronal and epithelial glutamate transporter and was previously
tested as a candidate for obsessive–compulsive disorder (OCD) by several research groups …

Meta‐analysis of association between obsessive‐compulsive disorder and the 3′ region of neuronal glutamate transporter gene SLC1A1

SE Stewart, C Mayerfeld, PD Arnold… - American Journal of …, 2013 - Wiley Online Library
The neuronal glutamate transporter gene SLC1A1 is a candidate gene for obsessive‐
compulsive disorder (OCD) based on linkage studies and convergent evidence implicating …

Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study

E Voyiaziakis, O Evgrafov, D Li, HJ Yoon… - Molecular …, 2011 - nature.com
Genetic association studies of SLC6A4 (SERT) and obsessive-compulsive disorder (OCD)
have been equivocal. We genotyped 1241 individuals in 278 pedigrees from the OCD …

Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder

CJ McDougle, CN Epperson, LH Price… - Molecular …, 1998 - nature.com
Obsessive compulsive disorder (OCD) is characterized by recurrent and intrusive thoughts
that are distressing (obsessions) and/or repetitive behaviors or mental acts that the person …