Molnupiravir for the treatment of COVID-19 outpatients: An updated meta-analysis

HA Cheema, SA Rab, M Butt, U Jafar, A Shahid… - Journal of Microbiology …, 2024 - Elsevier
Background The majority of available data on molnupiravir come from an unvaccinated
COVID-19 population. Therefore, we conducted this meta-analysis to integrate evidence …

Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study

J Liu, X Pan, S Zhang, M Li, K Ma, C Fan… - The Lancet Regional …, 2023 - thelancet.com
Summary Background Nirmatrelvir plus ritonavir (Paxlovid) reduced the risk of
hospitalization or death by 89% in high-risk, ambulatory adults with COVID-19. We aimed at …

[HTML][HTML] Population-based evaluation of the effectiveness of nirmatrelvir–ritonavir for reducing hospital admissions and mortality from COVID-19

KL Schwartz, J Wang, M Tadrous, BJ Langford… - Cmaj, 2023 - Can Med Assoc
Background: A randomized controlled trial involving a high-risk, unvaccinated population
that was conducted before the Omicron variant emerged found that nirmatrelvir–ritonavir …

Clinical outcomes following treatment for COVID-19 with nirmatrelvir/ritonavir and molnupiravir among patients living in nursing homes

BHM Ma, TCF Yip, GCY Lui, MSM Lai, E Hui… - JAMA Network …, 2023 - jamanetwork.com
Importance Older patients living in nursing homes are at very high risk of mortality after
getting COVID-19. Objective To evaluate outcomes following oral antiviral treatment for …

COVID-19 Therapeutics for Nonhospitalized Patients—Updates and Future Directions

KW Chew, PN Malani, RT Gandhi - JAMA, 2023 - jamanetwork.com
Antiviral therapeutics for COVID-19 in nonhospitalized patients prevent progression to
severe illness, hospitalization, and death. Despite their proven benefit, utilization of these …

Nirmatrelvir/ritonavir utilization for the treatment of non-hospitalized adults with COVID-19 in the National Veterans Affairs (VA) Healthcare System

HJ Appaneal, KL LaPlante, VV Lopes, C Martin… - Infectious Diseases and …, 2024 - Springer
Introduction Limited data exist regarding real-world utilization of nirmatrelvir/ritonavir. We
identified predictors of nirmatrelvir/ritonavir use among Veterans Affairs (VA) outpatients …

Molnupiravir for treatment of adults with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials

Y Gao, M Liu, Z Li, J Xu, J Zhang, J Tian - Clinical Microbiology and …, 2023 - Elsevier
Background The effects of molnupiravir in treating patients with non-severe COVID-19
remain uncertain. Objectives To evaluate the efficacy and safety of molnupiravir in adult …

Real-life comparison of mortality in patients with SARS-CoV-2 infection at risk for clinical progression treated with molnupiravir or nirmatrelvir plus ritonavir during the …

C Torti, PP Olimpieri, P Bonfanti, C Tascini… - The Lancet Regional …, 2023 - thelancet.com
Background Comparative data on mortality in COVID-19 patients treated with molnupiravir
or with nirmatrelvir plus ritonavir are inconclusive. We therefore compared all-cause …

[HTML][HTML] Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis

T Pitre, R Van Alstine, G Chick, G Leung, D Mikhail… - Cmaj, 2022 - Can Med Assoc
Background: Randomized trial evidence suggests that some antiviral drugs are effective in
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …

[HTML][HTML] Efficacy of Molnupiravir for the treatment of mild or moderate COVID-19 in adults: a meta-analysis

K Benaicha, RR Khenhrani, M Veer, S Devi… - Cureus, 2023 - ncbi.nlm.nih.gov
The aim of this meta-analysis is to evaluate the efficacy of molnupiravir among mild or
moderate COVID-19 patients. This meta-analysis was reported according to the guidelines …