Efficacy and safety of molnupiravir for the treatment of non-hospitalized adults with mild COVID-19: a randomized, open-label, parallel-group phase 3 trial

SK Tippabhotla, DS Lahiri, C Kandi - 2022 - papers.ssrn.com
Background: Molnupiravir is an oral prodrug with antiviral activity against severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2). Molnupiravir was initially developed for …

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
Background New treatments are needed to reduce the risk of progression of coronavirus
disease 2019 (Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is …

[HTML][HTML] Effectiveness of Nirmatrelvir-Ritonavir for the Prevention of COVID-19–Related Hospitalization and Mortality: A Systematic Literature Review

AS Cha-Silva, MB Gavaghan, T Bergroth… - American Journal of …, 2024 - journals.lww.com
Background: Nirmatrelvir/ritonavir (NMV/r) is an oral antiviral drug used to treat mild-to-
moderate coronavirus disease 2019 (COVID-19) in patients aged 12 years or older at high …

Identifying Veterans Who Benefit From Nirmatrelvir-Ritonavir: A Target Trial Emulation

L Yan, D Bui, Y Li, N Rajeevan… - Clinical Infectious …, 2024 - academic.oup.com
Background Nirmatrelvir-ritonavir is recommended for persons at risk for severe coronavirus
disease 2019 (COVID-19) but remains underutilized. Information on which eligible groups …

Nirmatrelvir and ritonavir for inpatients with severe or critical COVID-19 beyond five days of symptom onset: a propensity score-matched, multicenter, retrospective …

H Zhang, X Tan, Z Zhang, C Wang, H Shi, Y Li… - BMC Infectious …, 2024 - Springer
Background There is an urgent need for therapeutic strategies for inpatients with severe or
critical COVID-19. The evaluation of the clinical benefits of nirmatrelvir and ritonavir (Nmr/r) …

Association of nirmatrelvir–ritonavir with post-acute sequelae and mortality in patients admitted to hospital with COVID-19: a retrospective cohort study

H Wang, Y Wei, CT Hung, G Lin, X Jiang… - The Lancet Infectious …, 2024 - thelancet.com
Background Studies have established the short-term efficacy of nirmatrelvir–ritonavir in
managing COVID-19, yet its effect on post-COVID-19 condition, especially in patients …

Real-life experience of molnupiravir in hospitalized patients who developed SARS-CoV2-infection: preliminary results from CORACLE registry

T Lupia, S Corcione, N Shbaklo, L Boglione… - Antibiotics, 2022 - mdpi.com
Real-life experience of molnupiravir treatment is lacking, especially in people hospitalized
for underlying diseases not related to COVID-19. We conducted a retrospective analysis …

Comparative effectiveness of Paxlovid versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised patients: observational …

B Zheng, J Tazare, L Nab, A Mehrkar, B MacKenna… - medRxiv, 2023 - medrxiv.org
Objective To compare the effectiveness of Paxlovid vs. sotrovimab and molnupiravir in
preventing severe COVID-19 outcomes in non-hospitalised high-risk COVID-19 adult …

[HTML][HTML] Efficacy and tolerability of Sotrovimab, Molnupiravir and Nirmatrelvir/Ritonavir for non-hospitalized patients at high risk for COVID-19: a retrospective, single …

V Kauer, D Totschnig, M Augustin, M Karolyi, A Zoufaly… - 2023 - europepmc.org
Background: The use of outpatient antiviral treatment for high-risk patients with coronavirus
disease 19 (COVID-19) is crucial in preventing progression to severe COVID-19 and …

[HTML][HTML] Hospitalization among patients treated with molnupiravir: A retrospective study of administrative data

G Prajapati, A Das, Y Sun, E Fonseca - Clinical Therapeutics, 2023 - Elsevier
Purpose Molnupiravir is an oral antiviral agent authorized for emergency use to treat mild to
moderate cases of coronavirus disease 2019 (COVID-19) in adults at high risk for …