Anti-SARS-CoV-2 and anti-cytokine storm neutralizing antibody therapies against COVID-19: Update, challenges, and perspectives

CM Batista, L Foti - International Immunopharmacology, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has been declared by the World Health
Organization (WHO) as a pandemic since March 2020. This disease is caused by severe …

SARS-CoV-2 neutralizing antibody development strategies

BK Balcioğlu, MDİİ ÖncÜ, HÜ ÖztÜrk… - Turkish Journal of …, 2020 - journals.tubitak.gov.tr
In December 2019 a novel coronavirus was detected in Wuhan City of Hubei Province-
China. Owing to a high rate of transmission from human to human, the new virus called …

[PDF][PDF] Recent updates in the clinical trials of therapeutic monoclonal antibodies targeting cytokine storm for the management of COVID-19

S Patel, B Saxena, P Mehta - Heliyon, 2021 - cell.com
Clinical studies have identified a cytokine storm in the third stage of disease progression in
critical ill patients with coronavirus disease 2019 (COVID-19). Hence, effectively …

SARS-CoV-2 neutralizing antibodies for COVID-19 prevention and treatment

D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
Prophylactic and therapeutic drugs are urgently needed to combat coronavirus disease
2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective

Y Huang, H Sun, H Yu, S Li, Q Zheng… - Antibody …, 2020 - academic.oup.com
The rapid emergence of Coronavirus disease-2019 (COVID-19) caused by severe acute
respiratory syndrome 2 coronavirus (SARS-CoV-2) as a pandemic that presents an urgent …

Neutralizing antibody: a savior in the Covid-19 disease

SL Gupta, RK Jaiswal - Molecular biology reports, 2022 - Springer
Coronavirus outbreak was declared a pandemic by World Health Organization (WHO) in
March 2020. The pandemic has led to a devastating loss of life. It has shown us how …

Perspectives on the development of neutralizing antibodies against SARS-CoV-2

M Ho - Antibody therapeutics, 2020 - academic.oup.com
SARS-CoV-2 gains entry to human cells through its spike (S) protein binding to angiotensin-
converting enzyme 2 (ACE2). Therefore, the receptor binding domain (RBD) of the S protein …

Monoclonal antibody therapies in the management of SARS-CoV-2 infection

E Miguez-Rey, D Choi, S Kim, S Yoon… - Expert Opinion on …, 2022 - Taylor & Francis
ABSTRACT Introduction Neutralizing antibodies (NAbs) that target key domains of the spike
protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have …

Emerging antibody-based therapeutics against SARS-CoV-2 during the global pandemic

Y Sun, M Ho - Antibody therapeutics, 2020 - academic.oup.com
SARS-CoV-2 antibody therapeutics are being evaluated in clinical and preclinical stages. As
of 11 October 2020, 13 human monoclonal antibodies targeting the SARS-CoV-2 spike …

Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV

W Jiang, J Wang, S Jiao, C Gu, W Xu, B Chen, R Wang… - MAbs, 2021 - Taylor & Francis
The global pandemic of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has resulted in widespread social and economic disruption …