Traumatic injury to the central nervous system initiates inflammatory processes that are
implicated in secondary tissue damage. These processes include the synthesis of …

The central nervous system (CNS) is an immune-privileged site where the role of immune
cells and mediators in traumatic brain injury is poorly understood. Previously we have …

Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to
brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged …

Abstract Interleukin‐1β (IL‐1β) may play a central role in the inflammatory response
following traumatic brain injury (TBI). We subjected 91 mice to controlled cortical impact …

Controlling the extent of inflammatory responses following brain injury may be beneficial
since posttraumatic intracranial inflammation has been associated with adverse outcome. In …

Background: Cytokines have been shown to be involved in traumatic brain injury (TBI). We
investigated the independent association between serum levels of IL-10 and TNF-α and …

Background: Pro-inflammatory cytokines play an essential role in maintenance of normal
brain function as well as in repair after traumatic brain injuries (TBI). However, massive and …

The effects of the anti-inflammatory cytokine, IL-10, on brain injury following permanent focal
ischemia were determined. Rats subjected to occlusion of the right middle cerebral artery …

In these studies, we examined the neuroprotective effects of the potent antiinflammatory
cytokine interleukin-10 (IL-10) following spinal cord injury (SCI). Neuroprotection was …

Traumatic brain injury (TBI) is a leading cause of mortality and disability. Acute postinjury
insults after TBI, such as hypoxia, contribute to secondary brain injury and worse clinical …