Bacteriophages present unique features that enable targeted killing of bacteria, including
strains resistant to many antibiotics. However, phage pharmacokinetics and …

The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections
has been ongoing clinically for approximately 100 years. Despite that long history, the …

Pharmacology can be differentiated into two key aspects, pharmacodynamics and
pharmacokinetics. Pharmacodynamics describes a drug's impact on the body while …

Antimicrobial resistance remains a critical global health concern, necessitating the
investigation of alternative therapeutic approaches. With the diminished efficacy of …

Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …

There is a renaissance of interest in the antimicrobial potential of phages as more
pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is …

The discovery of bacterial viruses approximately 100 years ago fairly quickly led to their use
as antibacterial agents. For roughly two decades–early 1920s to early 1940s …

Introduction: In light of the emergence of antibiotic-resistant bacteria, phage (bacteriophage)
therapy has been recognized as a potential alternative or addition to antibiotics in Western …

Due to the rise of multidrug-resistant infections in humans, phage therapy is gaining
renewed attention in Western medicine. Despite the increasing number of publications …

Background The increasing emergence of antimicrobial resistance worldwide has led to
renewed interest in phage therapy. Unlike antibiotics, the lack of pharmacokinetics …