Previous studies have demonstrated that excessive free radicals play an essential role in the
initiation and progression of epilepsy and that a novel exogenous free radical scavenger …

Epilepsy is a severe and chronic neurological disease. Edaravone is an effective free radical
scavenger and has been reported to prevent neuronal loss induced by Kainate (KA) …

Previous studies have demonstrated that kainic acid (KA)-induced seizures can cause the
enhancement of excitation and lead to neuronal death in rat hippocampus. Co-activation of …

Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …

Evidence points towards oxidative stress and neuroinflammation being major processes
associated with brain dysfunction in epilepsy. Salidroside reportedly possesses anti …

Preclinical and clinical studies have demonstrated that a free radical scavenger edaravone
has neuroprotective effects on ischemic stroke but the underlying mechanism is not fully …

Oxidative stress resulting from excessive free-radical release is likely implicated in the
initiation and progression of epilepsy. Therefore, antioxidant therapies have received …

Status epilepticus (SE) leads to irreversible neuronal damage and consists of a complex
pathogenesis that involves oxidative stress and subsequent autophagy. Rosiglitazone has …

The present study aimed to investigate whether Na+, K+-ATPase activity and
phosphorylation state of the catalytic α subunit are altered by pentylenetetrazol (PTZ) …

Epilepsy remains a major medical problem for which there is no effective treatment.
Oxidative damage plays an important role in epilepsy pathogenesis and may represent a …