Benign prostatic hyperplasia as a progressive disease: a guide to the risk factors and options for medical management

M Emberton, EB Cornel, PF Bassi… - … journal of clinical …, 2008 - Wiley Online Library
Benign prostatic hyperplasia (BPH) is a complex disease that is progressive in many men.
BPH is commonly associated with bothersome lower urinary tract symptoms; progressive …

The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the …

CG Roehrborn, P Siami, J Barkin, R Damião… - European urology, 2010 - Elsevier
BACKGROUND: Combination therapy with dutasteride and tamsulosin provides significantly
greater benefit than either monotherapy for various patient-reported outcomes in men with …

The progression of benign prostatic hyperplasia: examining the evidence and determining the risk

JB Anderson, CG Roehrborn, JA Schalken… - European …, 2001 - karger.com
Background: Benign prostatic hyperplasia (BPH) is often associated with enlargement of the
prostate gland, lower urinary tract symptoms, decreased urinary flow and a reduced quality …

Clinical outcomes after combined therapy with dutasteride plus tamsulosin or either monotherapy in men with benign prostatic hyperplasia (BPH) by baseline …

CG Roehrborn, J Barkin, P Siami, A Tubaro… - BJU …, 2011 - Wiley Online Library
What's known on the subject? and What does the study add? Treatment of benign prostatic
hyperplasia (BPH) centres on two drug classes, 5α‐reductase inhibitors and α‐blockers. The …

Benign prostatic hyperplasia: when to'watch and wait,'when and how to treat.

A Levy, GP Samraj - Cleveland Clinic journal of medicine, 2007 - europepmc.org
Benign prostatic hyperplasia (BPH) is a clinical diagnosis. While BPH is a common cause of
lower urinary tract symptoms (LUTS) in men, LUTS can signify a number of other disease …

BPH progression: concept and key learning from MTOPS, ALTESS, COMBAT, and ALF‐ONE

CG Roehrborn - BJU international, 2008 - Wiley Online Library
Benign prostatic hyperplasia (BPH) represents a significant burden in ageing men due to
frequently associated lower urinary tract symptoms (LUTS), which may impair quality of life …

Meta-analysis of the efficacy and safety of combination of tamsulosin plus dutasteride compared with tamsulosin monotherapy in treating benign prostatic hyperplasia

Z Zhou, Y Cui, J Wu, R Ding, T Cai, Z Gao - BMC urology, 2019 - Springer
Background We performed a meta-analysis to confirm the efficacy and safety of the
combination of tamsulosin plus dutasteride compared with tamsulosin monotherapy in …

Optimising the medical management of benign prostatic hyperplasia

M Marberger, R Harkaway, J de la Rosette - European urology, 2004 - Elsevier
As demographics change, with the elderly constituting an increasing proportion of the
population, the prevalence of benign prostatic hyperplasia (BPH) is increasing, with a …

Efficacy and safety of a fixed‐dose combination of dutasteride and tamsulosin treatment (Duodart®) compared with watchful waiting with initiation of tamsulosin …

CG Roehrborn, I Oyarzabal Perez, EPM Roos… - BJU …, 2015 - Wiley Online Library
Objective To investigate whether a fixed‐dose combination (FDC) of 0.5 mg dutasteride and
0.4 mg tamsulosin is more effective than watchful waiting with protocol‐defined initiation of …

Benign prostatic hyperplasia in primary care: what you need to know

AL Burnett, AJ Wein - The Journal of urology, 2006 - Elsevier
PURPOSE: We reviewed recent literature and treatment guidelines regarding the
prevalence, pathophysiology, and management of BPO related to BPH; and management of …