X Zang, R Luo, N Song, TK Chen… - … in Mass Spectrometry …, 2005 - Wiley Online Library
An on‐line solid‐phase extraction liquid chromatography/tandem mass spectrometry (SPE LC/MS/MS) assay using a newly developed SPE column and a monolithic column was …
CR Mallet, JR Mazzeo, U Neue - Rapid Communications in …, 2001 - Wiley Online Library
Abstract Several configurations using 6‐and 10‐port switching valves were studied for high flow, on‐line extraction of rat plasma coupled to an electrospray triple quadrupole mass …
A Schellen, B Ooms, D van de Lagemaat… - … of Chromatography B, 2003 - Elsevier
A generic method was developed for the fast determination of a wide range of drugs in serum or plasma. The methodology comprises generic solid-phase extraction, on-line …
Y Hsieh, MS Bryant, G Gruela… - Rapid …, 2000 - Wiley Online Library
A sensitive, efficient, high throughput, direct injection bioanalytical method based on a single column and high‐performance liquid chromatography (HPLC) with tandem mass …
XH Chen, JP Franke, K Ensing… - Journal of analytical …, 1993 - academic.oup.com
A fully automated solid-phase extraction (SPE) method for drug screening is described. The extraction of 19 toxicologically relevant drugs from pretreated plasma and pretreated whole …
YJ Xue, JB Akinsanya, J Liu… - … Communications in Mass …, 2006 - Wiley Online Library
A simplified protein precipitation/mixed‐mode cation‐exchange solid‐phase extraction (PPT/SPE) procedure has been investigated. A mixture of acetonitrile and methanol along …
Quantitation of low concentration of drugs, metabolites and endogenous compounds in plasma has always been a difficulty and challenge task for analytical chemists in biomedical …
S Kawano, M Takahashi, T Hine… - … Journal Devoted to …, 2005 - Wiley Online Library
A novel methylcellulose‐immobilized restricted access media column with strong cation‐ exchange groups on an internal surface (MC‐SCX) was evaluated for the direct injection …
CR Mallet, Z Lu, J Mazzeo… - Rapid Communications in …, 2002 - Wiley Online Library
Two on‐line configurations using multiple 6‐and 10‐port valves were investigated for high‐ flow on‐line extraction of a basic drug in rat plasma and human urine using a reversed …